Bus from Houston, US to Greenville, SC: Tickets & Schedules

Next departures

Next departures for Houston to Greenville on December 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Baytown, 6800 Thompson Rd
1116 Woodruff RdCheapest
Expreso
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)Fastest
Amtrak
Amtrak Station
Greenville StationNo tags
Greyhound Lines, Inc.
Houston Bus Station
1116 Woodruff RdNo tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff RdNo tags

Last refresh of the prices: Last Sunday at 8:10 AM CST.

Compare 2 ways to go from Houston to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 6 hours 40 minutes and with fares starting at just $115, it presents an excellent value for a comfortable ride.

22bus per day
1d 6hAverage Duration
838 milesDistance
34kgCO₂ emissions
Average Price$115 - $511Average Duration1d 6h
34kg CO₂e
Average Price$189 - $1,143Average Duration1d 13h
122kg CO₂e

Frequently asked questions about traveling from Houston, US to Greenville, SC by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Houston to Greenville?

    The cheapest bus tickets from Houston to Greenville start from $115. The average price for this route is around $163. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Houston to Greenville?

    The average bus trip duration from Houston to Greenville is 1d 6h, covering a distance of 838 miles (1351 km). The quickest bus can get you there in 15h 11m and is operated by Tornado Bus.

  3. Which bus companies service the Houston to Greenville route?

    Several major bus companies operate on this route with 22 buses available per day, including services from Greyhound, Tornado Bus, Amtrak, FlixBus, Valley Transit.

  4. What is the earliest and latest departure time for the bus from Houston to Greenville?

    The earliest bus departs from Houston to Greenville at 5:00am. And the latest bus departs at 11:20pm.

  5. What are the CO₂ emissions for the bus trip from Houston to Greenville?

    A bus trip from Houston to Greenville generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Houston to Greenville?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.

  7. Which bus company has the best Wi-Fi from Houston to Greenville?

    Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company has the most timely service from Houston to Greenville?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Houston to Greenville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/02
$148
12/03
$183
Today
$135
12/05
$138
12/06
$143
12/07
$138
12/08
$131
12/09
$131
busbud logoThe cheapest trip from Houston, US to Greenville, SC was searched and found on Dec 8, 2025 with a price of $131

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Greenville, SC, as early as possible.

You can expect to pay from $131 to $2,273 for a bus ticket from Houston, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $131 which is on 2025-12-08.

Usually Tornado Bus, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Houston, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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