Bus Tickets from Indianapolis to St Louis

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TodayJun 3
TomorrowJun 4
ThuJun 5
FriJun 6
SatJun 7
SunJun 8
MonJun 9
from US$42
TueJun 10

Next departures to St Louis

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 9 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: June 9 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 9 at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: June 9 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: June 9 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: June 9 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 9 at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: June 9 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: June 9 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: June 9 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 6:11 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Indianapolis to St Louis

Bus
Average PriceUS$37 - US$193Average Duration4h 55m
9kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$89 - US$456Average Duration14h 7m
34kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to St Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St Louis. The journey takes about 4 hours 55 minutes, and with fares starting at just US$37, it presents an excellent value for a comfortable ride.

4bus per day
4h 55mAverage Duration
US$37Cheapest ticket
9kgCO₂ emissions

Bus Indianapolis to St Louis: Trip Overview

Average Ticket PriceUS$45
Average Bus Trip Duration4h 55m
Number of daily buses4
Earliest bus departure3:30am
Distance371 km
Latest bus departure8:05pm

Indianapolis to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to St Louis.

We make sure you can find a bus service from Indianapolis to St Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - St Louis

  1. How long does it take to get to St Louis from Indianapolis by bus?

    The bus ride from Indianapolis to St Louis takes 4h 55m, on average. The fastest bus on this trip will get to St Louis in 3h 55m

  2. What is the distance between Indianapolis and St Louis?

    The distance between Indianapolis and St Louis is approximately 371 km (230 miles).

  3. What are the departure and arrival locations for buses traveling from Indianapolis to St Louis?

    Buses departing from Greyhound Amtrak Station in Indianapolis will take you to Gateway Station in St Louis.

  4. What is the cheapest way to get from Indianapolis to St Louis?

    Taking the bus is the most budget-friendly option to travel from Indianapolis to St Louis. Starting at US$37, this bus is the most cost-effective option for your journey.

  5. How much is the bus from Indianapolis to St Louis?

    You can expect to pay around US$45 for the bus ride from Indianapolis to St Louis.

  6. Is it possible to travel by overnight bus from Indianapolis to St Louis?

    Yes! If you're heading from Indianapolis to St Louis, you'll find buses departing until 8:05pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-01
No data
06-02
US$34
Today
US$32
06-04
US$34
06-05
US$32
06-06
No data
06-07
US$34
06-08
US$32
busbud logoThe cheapest trip from Indianapolis to St Louis was searched and found on Jun 3, 2025 with a price of US$32

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to St Louis, as early as possible.

You can expect to pay from US$32 to US$327 for a bus ticket from Indianapolis to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$32 which is on 2025-06-05.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to St Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to St Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to St Louis while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Indianapolis to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to St Louis

You can also go to St Louis by train

Train from Indianapolis to St Louis

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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