Bus Tickets from Philadelphia, PA to Syracuse, US

Next bus departures

Next departures for Philadelphia to Syracuse on November 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)Cheapest
FlixBusBus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)Fastest
Greyhound Lines, Inc.Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)No tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Syracuse (Regional Transportation Center)No tags
FlixBusBus
Philadelphia, 199 Spring Garden St
Syracuse (Regional Transportation Center)No tags

Last refresh of the prices: Yesterday at 10:32 PM EST.

Compare 2 ways to go from Philadelphia to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 8 hours 40 minutes, and with fares starting at just $70, it presents an excellent value for a comfortable ride.

41bus per day
8h 40mAverage Duration
357 kmDistance
9kgCO₂ emissions
Bus
Average Price$70 - $510Average Duration8h 40m
9kg CO₂e
Train
Average Price$101 - $1,696Average Duration9h 4m
32kg CO₂e

Frequently asked questions about travelling from Philadelphia, PA to Syracuse, US by bus

  1. What is the travel distance from Philadelphia to Syracuse?

    The distance between Philadelphia and Syracuse is around 355 km (220 miles).

  2. What are the departure and arrival locations for buses traveling from Philadelphia to Syracuse?

    Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Regional Transportation Center, in Syracuse.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-18
$119
11-19
$119
Today
$137
11-21
$165
11-22
$119
11-23
$155
11-24
$139
11-25
$125
busbud logoThe cheapest trip from Philadelphia, PA to Syracuse, US was searched and found on Nov 18, 2025 with a price of $119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Syracuse, US, as early as possible.

You can expect to pay from $119 to $221 for a bus ticket from Philadelphia, PA to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $119 which is on 2025-11-22.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Philadelphia, PA to Syracuse, US?

busbud logoThe bus is the cheapest travel choice for this destination

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