Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Peter Pan + Adirondack Trailways | Bus | Philadelphia Bus Terminal | Amtrak Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia Bus Station | Syracuse (Regional Transportation Center) | Fastest | ||||
 | Bus | Philadelphia Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Philadelphia Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
 | Bus | Philadelphia Bus Station | Syracuse (Regional Transportation Center) | No tags |
Last refresh of the prices: Yesterday at 11:54 PM EDT.
Compare 2 ways to go from Philadelphia to Syracuse
Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 8 hours 25 minutes and with fares starting at just $52, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and Syracuse?
Stops in Philadelphia
- A
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - E
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210 - D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
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Frequently asked questions about traveling from Philadelphia, PA to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Philadelphia to Syracuse?
The cheapest bus tickets from Philadelphia to Syracuse start from $52. The average price for this route is around $68. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to Syracuse?
The average bus trip duration from Philadelphia to Syracuse is 8h 25m, covering a distance of 221 miles (357 km). The quickest bus can get you there in 6h 35m and is operated by FlixBus.
Which bus companies service the Philadelphia to Syracuse route?
What is the earliest and latest departure time for the bus from Philadelphia to Syracuse?
The earliest bus departs from Philadelphia to Syracuse at 12:25am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Philadelphia to Syracuse?
A bus trip from Philadelphia to Syracuse generates an estimated 8.908975 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Philadelphia to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12791 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Syracuse?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Philadelphia to Syracuse?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Syracuse?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to Syracuse, US was searched and found on Jun 15, 2026 with a price of $54To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Syracuse, US, as early as possible.
You can expect to pay from $54 to $191 for a bus ticket from Philadelphia, PA to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2026-06-15.
Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Philadelphia, PA to Syracuse, US?
The Bus is the cheapest travel choice for this destination
