Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Ómnibus | Estación Terminal de Ómnibius, Santa Fe | Cheapest | ||||
| Bus | Terminal de Ómnibus | Estación Terminal de Ómnibius, Santa Fe | Fastest | ||||
| Bus | Terminal de Ómnibus | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
| Bus | Terminal de Ómnibus | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
| Bus | Terminal de Ómnibus | Estación Terminal de Ómnibius, Santa Fe | No tags |
Last refresh of the prices: Last Wednesday at 1:43 AM -03.
Get from Puerto Iguazú to Santa Fe
The journey takes about 16 hours 45 minutes, and with fares starting at just $92, it presents an excellent value for a comfortable ride.
Where are the popular stops in Puerto Iguazú and Santa Fe?
Stops in Puerto Iguazú
- AAv. Misiónes 1-99, N3370FBA Puerto Iguazú, Misiónes, Argentina
- B
Puerto Iguazú Accesso
RN12, Puerto Iguazú, Misiónes, Argentina
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Frequently asked questions about travelling from Puerto Iguazú to Santa Fe, AR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Puerto Iguazú to Santa Fe?
The cheapest bus tickets from Puerto Iguazú to Santa Fe start from $92. The average price for this route is around $134. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Puerto Iguazú to Santa Fe?
The average bus travel time from Puerto Iguazú to Santa Fe is 16h 45m, covering a distance of 900 km. The quickest bus can get you there in 16h and is operated by Rio Uruguay.
Which bus companies service the Puerto Iguazú to Santa Fe route?
Several major bus companies operate on this route with 4 buses available per day, including services from Rio Uruguay, 20 de Junio, Expreso Singer.
What are the earliest and latest departure times for the bus from Puerto Iguazú to Santa Fe?
The earliest bus departs from Puerto Iguazú to Santa Fe at 7:30am. And the latest bus departs at 4:00pm.
What are the CO₂ emissions for the bus trip from Puerto Iguazú to Santa Fe?
A bus trip from Puerto Iguazú to Santa Fe generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Puerto Iguazú to Santa Fe?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 586 reviews.
Which bus company has the best Wi-Fi from Puerto Iguazú to Santa Fe?
Based on Busbud reviews, the bus company 20 de Junio has the highest Wi-Fi rating with a score of 2.3.
Which bus company has the best on-time performance from Puerto Iguazú to Santa Fe?
According to Busbud traveller reviews, the most punctual bus company on this route is 20 de Junio, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Puerto Iguazú to Santa Fe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Puerto Iguazú to Santa Fe, AR was searched and found on Dec 13, 2025 with a price of $101To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Puerto Iguazú to Santa Fe, AR, as early as possible.
You can expect to pay from $101 to $142 for a bus ticket from Puerto Iguazú to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $104 which is on 2025-12-17.
Usually Rio Uruguay will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
