Find coaches from Puerto Iguazú to Santa Fe, AR

Find affordable coach tickets from Puerto Iguazú to Santa Fe, AR with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today5 Jul
Tomorrow6 Jul
from US$60
Mon7 Jul
Tue8 Jul
Wed9 Jul
Thu10 Jul
Fri11 Jul
Sat12 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 6 July at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: 7 July at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Expreso SingerExpreso Singer
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 6 July at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: 7 July at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: 6 July at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: 7 July at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: 6 July at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: 7 July at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: 6 July at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: 7 July at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Puerto Iguazú to Santa Fe: Trip Overview

Average ticket priceUS$94
Average bus trip duration16h 45m
Number of daily buses4
Earliest bus departure07:30
Distance558 miles
Latest bus departure16:00

Puerto Iguazú to Santa Fe Bus

With Busbud, comparing and booking tickets for a bus from Puerto Iguazú to Santa Fe is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Puerto Iguazú to Santa Fe from the most reliable bus companies operating this trip.

Discover how much the bus trip from Puerto Iguazú to Santa Fe will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Puerto Iguazú - Santa Fe, AR

  1. How far is Santa Fe from Puerto Iguazú by coach?

    The distance between Puerto Iguazú and Santa Fe by coach is approximately 558 miles (900 km).

  2. Is there a way to reach Santa Fe from Puerto Iguazú without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/07
US$52
04/07
US$76
Today
No data
06/07
US$51
07/07
No data
08/07
No data
09/07
No data
10/07
No data
busbud logoThe cheapest trip from Puerto Iguazú to Santa Fe was searched and found on 6 Jul 2025 with a price of US$51

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Puerto Iguazú to Santa Fe as early as possible.

You can expect to pay from US$51 to US$87 for a bus ticket from Puerto Iguazú to Santa Fe based on the last 2 days. You can expect to find the cheapest price for the trip at US$51, which is on 2025-07-06.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Puerto Iguazú to Santa Fe.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Puerto Iguazú to Santa Fe, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Puerto Iguazú to Santa Fe will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Puerto Iguazú to Santa Fe, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Puerto Iguazú by bus?

Bus from Puerto Iguazú to Santa Fe

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Puerto Iguazú

Buses Leaving from Puerto Iguazú

Buses Going to Puerto Iguazú

Popular Buses Connecting Santa Fe

Buses Leaving from Santa Fe

Buses Going to Santa Fe