Bus Tickets from Puerto Iguazú to Santa Fe

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TodayMay 7
from $65
TomorrowMay 8
from $65
FriMay 9
SatMay 10
SunMay 11
MonMay 12
TueMay 13
WedMay 14

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 8 at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: May 9 at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: La 20 de JunioLa 20 de Junio
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 8 at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: May 9 at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: May 9 at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: May 9 at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: La 20 de JunioLa 20 de Junio
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Puerto Iguazú
    Departure location: Terminal de Ómnibus
    Arrival time: May 9 at
    Destination city: Santa Fe
    Destination location: Estación Terminal de Ómnibius, Santa Fe
    Operated by: Expreso SingerExpreso Singer
    Vehicle: BusDuration:

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Bus Puerto Iguazú to Santa Fe: Trip Overview

Average ticket price$95
Average bus trip duration16h 45m
Number of daily buses4
Earliest bus departure7:30am
Distance558 miles (899 km)
Latest bus departure4:00pm

Puerto Iguazú to Santa Fe Bus

With Busbud, comparing and booking tickets for a bus from Puerto Iguazú to Santa Fe is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

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Frequently asked questions for your trip Puerto Iguazú - Santa Fe

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/05
No data
05/06
No data
Today
$64
05/08
$64
05/09
No data
05/10
$68
05/11
$72
05/12
$72
busbud logoThe cheapest trip from Puerto Iguazú to Santa Fe was searched and found on May 8, 2025 with a price of $64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Puerto Iguazú to Santa Fe, as early as possible.

You can expect to pay from $64 to $115 for a bus ticket from Puerto Iguazú to Santa Fe based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-05-08.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Puerto Iguazú to Santa Fe.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Puerto Iguazú to Santa Fe, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Puerto Iguazú to Santa Fe will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Puerto Iguazú to Santa Fe, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Puerto Iguazú by bus?

Bus from Puerto Iguazú to Santa Fe

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