Find coaches from Itajaí to Santiago, BR

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Today3 Jul
Tomorrow4 Jul
Sat5 Jul
Sun6 Jul
Mon7 Jul
Tue8 Jul
from US$73
Wed9 Jul
Thu10 Jul

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 8 July at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: 9 July at
    Destination city: Santiago
    Destination location: Estação Rodoviária De Santiago
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: 8 July at
    Departure city: Itajaí
    Departure location: Itajaí Bus Terminal
    Arrival time: 9 July at
    Destination city: Santiago
    Destination location: Estação Rodoviária De Santiago
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:

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Bus Itajaí to Santiago: Trip Overview

Average ticket priceUS$69
Average bus trip duration16h 45m
Number of daily buses1
Earliest bus departure20:00
Distance407 miles

Itajaí to Santiago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Itajaí to Santiago.

Bus service from Itajaí to Santiago will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Itajaí, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Itajaí - Santiago, BR

  1. What's the distance between Itajaí and Santiago by coach?

    The distance between Itajaí and Santiago by coach is approximately 409 miles (659 km).

  2. How can I travel from Itajaí to Santiago avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/07
US$59
02/07
No data
Today
No data
04/07
No data
05/07
No data
06/07
No data
07/07
No data
08/07
US$62
busbud logoThe cheapest trip from Itajaí to Santiago was searched and found on 1 Jul 2025 with a price of US$59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santiago as early as possible.

You can expect to pay from US$59 to US$78 for a bus ticket from Itajaí to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at US$62, which is on 2025-07-08.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Itajaí to Santiago but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Itajaí to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Itajaí to Santiago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Itajaí to Santiago.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Itajaí by bus?

Bus from Itajaí to Santiago

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