Find coaches from Louisville to Wytheville

Next departures

Next departures from Louisville to Wytheville on 14 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Louisville, KY
Wytheville Bus StationCheapest
Greyhound Lines, Inc.
Louisville, KY
Wytheville Bus StationFastest

Last refresh of the prices: Today at 02:59 EDT.

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Bus Louisville to Wytheville: Trip Overview

Average ticket priceUS$63
Average bus trip duration12h 5m
Number of daily buses2
Earliest bus departure14:20
Distance283 miles
Latest bus departure15:05

Louisville to Wytheville Bus

Busbud helps you find a bus from Louisville to Wytheville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Louisville to Wytheville.

Whether it is cheap bus tickets or more luxurious buses going to Wytheville from Louisville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Louisville - Wytheville

  1. How far is Wytheville from Louisville by coach?

    The journey from Louisville to Wytheville by coach covers an approximate distance of 271 miles (438 km).

  2. Is there a way to reach Wytheville from Louisville without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
No data
12/10
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Today
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14/10
US$91
15/10
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16/10
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17/10
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18/10
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busbud logoThe cheapest trip from Louisville to Wytheville was searched and found on 14 Oct 2025 with a price of US$91

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Wytheville as early as possible.

You can expect to pay from US$91 to US$91 for a bus ticket from Louisville to Wytheville based on the last 2 days. You can expect to find the cheapest price for the trip at US$91, which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Louisville and Wytheville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Louisville to Wytheville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Louisville to Wytheville.

Make a music playlist for your bus ride from Louisville to Wytheville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Louisville by bus?

Bus from Wytheville to Louisville

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