Cheap buses leaving Friday
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: 1 August atDeparture city: MexicaliDeparture location: Mexicali Bus StationArrival time: 1 August atDestination city: Santa AnaDestination location: Santa Ana Col Del RioOperated by: Tufesa
Vehicle: BusDuration: - Departure time: 1 August atDeparture city: MexicaliDeparture location: Mexicali Bus StationArrival time: 1 August atDestination city: Santa AnaDestination location: Santa Ana Col Del RioOperated by: TufesaVehicle: BusDuration:
- Departure time: 1 August atDeparture city: MexicaliDeparture location: Mexicali Bus StationArrival time: 1 August atDestination city: Santa AnaDestination location: Santa Ana Col Del RioOperated by: TufesaVehicle: BusDuration:
- Departure time: 1 August atDeparture city: MexicaliDeparture location: Mexicali Bus StationArrival time: 1 August atDestination city: Santa AnaDestination location: Santa Ana Col Del RioOperated by: TufesaVehicle: BusDuration:
- Departure time: 1 August atDeparture city: MexicaliDeparture location: Mexicali Bus StationArrival time: 2 August atDestination city: Santa AnaDestination location: Santa Ana Col Del RioOperated by: TufesaVehicle: BusDuration:
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Bus Mexicali to Santa Ana, SON, MX: Trip Overview
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Based on 674 reviews, the company was rated 3.4 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the timeliness. Tufesa ticket prices on this trip start at US$59
Mexicali to Santa Ana Bus
With Busbud, comparing and booking tickets for a bus from Mexicali to Santa Ana is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Mexicali to Santa Ana from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from Mexicali, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Mexicali and Santa Ana?
Frequently asked questions on the trip Mexicali - Santa Ana, SON, MX
What's the distance between Mexicali and Santa Ana by coach?
The distance between Mexicali and Santa Ana by coach is approximately 293 miles (472 km).
How can I travel from Mexicali to Santa Ana avoiding air travel?
You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexicali to Santa Ana, SON, MX was searched and found on 28 Jul 2025 with a price of US$54To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Santa Ana, SON, MX as early as possible.
You can expect to pay from US$54 to US$55 for a bus ticket from Mexicali to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at US$55, which is on 2025-08-01.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Mexicali to Santa Ana.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexicali to Santa Ana, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexicali to Santa Ana.
Make a music playlist for your bus ride from Mexicali to Santa Ana, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top travelled bus routes
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