Bus Tickets from Mexicali to Santa Ana (SON), MX

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TodayJun 5
TomorrowJun 6
from US$54
SatJun 7
SunJun 8
MonJun 9
TueJun 10
WedJun 11
ThuJun 12

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 6 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 6 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: June 6 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 6 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: June 6 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 6 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: June 6 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 7 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: June 6 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 7 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:

Last refresh of the prices: Last Sunday at 10:16 AM PDT.

Prices and availability are subject to change.

Accepted payments

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Bus Mexicali to Santa Ana: Trip Overview

Average Ticket PriceUS$54
Average Bus Trip Duration7h 20m
Number of daily buses11
Earliest bus departure1:00am
Distance473 km
Latest bus departure11:59pm

Mexicali to Santa Ana Bus

With Busbud, comparing and booking tickets for a bus from Mexicali to Santa Ana is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Mexicali to Santa Ana from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from Mexicali, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Mexicali - Santa Ana (SON), MX

  1. How long is the bus trip from Mexicali to Santa Ana?

    The typical travel time from Mexicali to Santa Ana by bus is around 7h 20m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 6h 50m.

  2. How far is Mexicali from Santa Ana?

    The distance between Mexicali and Santa Ana is around 472 km (293 miles).

  3. What are the departure and arrival locations for buses traveling from Mexicali to Santa Ana?

    Buses traveling this route start their trip at Terminal de Autobuses de Mexicali, in Mexicali, and end it at Parada de Autobuses de Santa Ana, in Santa Ana.

  4. What is the cheapest way to go from Mexicali to Santa Ana?

    The least expensive way to go from Mexicali to Santa Ana would be going by bus. Starting at US$52, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Mexicali to Santa Ana?

    Taking the bus from Mexicali to Santa Ana costs on average US$54.

  6. Can I take an overnight bus from Mexicali to Santa Ana?

    Yes! Catch buses leaving from Mexicali until 11:59pm and reaching Santa Ana on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-03
No data
06-04
No data
Today
No data
06-06
US$49
06-07
No data
06-08
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06-09
No data
06-10
US$49
busbud logoThe cheapest trip from Mexicali to Santa Ana was searched and found on Jun 6, 2025 with a price of US$49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Santa Ana, as early as possible.

You can expect to pay from US$49 to US$49 for a bus ticket from Mexicali to Santa Ana based on the last 2 days. You can expect to find the cheapest price for the trip at US$49 which is on 2025-06-06.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Mexicali to Santa Ana.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexicali to Santa Ana, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexicali to Santa Ana.

Make a music playlist for your bus ride from Mexicali to Santa Ana, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Mexicali by bus?

Bus from Mexicali to Santa Ana

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