Bus from Mexicali to Santa Ana, SON, MX: Tickets & Schedules

Previously seen trips

Next departures for Mexicali to Santa Ana on November 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
TufesaBus
Mexicali Bus Station
Santa Ana Col Del RioNo tags
TufesaBus
Mexicali Bus Station
Santa Ana Col Del RioNo tags
TufesaBus
Tufesa
Santa Ana Col Del RioNo tags
TufesaBus
Tufesa
Santa Ana Col Del RioNo tags
TufesaBus
Mexicali Bus Station
Santa Ana Col Del RioNo tags

Compare 2 ways to go from Mexicali to Santa Ana

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Santa Ana. The journey takes about 7 hours 16 minutes, and with fares starting at just $85, it presents an excellent value for a comfortable ride.

13bus per day
7h 16mAverage Duration
467 kmDistance
12kgCO₂ emissions
Bus
Average Price$85 - $97Average Duration7h 16m
12kg CO₂e
Carpool
Average Price$59 - $59Average Duration8h 20m
20kg CO₂e

Frequently asked questions about travelling from Mexicali to Santa Ana, SON, MX by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Mexicali to Santa Ana?

    The cheapest bus tickets from Mexicali to Santa Ana start from $85. The average price for this route is around $88. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Mexicali to Santa Ana?

    The average bus travel time from Mexicali to Santa Ana is 7h 16m, covering a distance of 467 km. The quickest bus can get you there in 6h 15m and is operated by Aguacaliente.

  3. Which bus companies service the Mexicali to Santa Ana route?

    Several major bus companies operate on this route with 13 buses available per day, including services from Tufesa, Interbus de Sinaloa, Aguacaliente.

  4. What are the earliest and latest departure times for the bus from Mexicali to Santa Ana?

    The earliest bus departs from Mexicali to Santa Ana at 2:00am. And the latest bus departs at 11:59pm.

  5. What are the CO₂ emissions for the bus trip from Mexicali to Santa Ana?

    A bus trip from Mexicali to Santa Ana generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Mexicali to Santa Ana?

    According to Busbud customers, the highest-rated bus company on this route is Interbus de Sinaloa, with an average rating of 3.6 out of 5 stars based on 3 reviews.

  7. Which bus company has the best Wi-Fi from Mexicali to Santa Ana?

    Based on Busbud reviews, the bus company Tufesa has the highest Wi-Fi rating with a score of 3.0.

  8. Which bus company has the best on-time performance from Mexicali to Santa Ana?

    According to Busbud traveller reviews, the most punctual bus company on this route is Tufesa, with a punctuality rating of 2.7 out of 5 stars.

  9. Which bus company has the cleanest buses from Mexicali to Santa Ana?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tufesa, with a cleanliness rating of 4.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-25
$79
11-26
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Today
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11-28
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11-29
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11-30
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12-01
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busbud logoThe cheapest trip from Mexicali to Santa Ana, SON, MX was searched and found on Nov 25, 2025 with a price of $79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Santa Ana, SON, MX, as early as possible.

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