Find coaches from Santa Ana, US to Mesa

Today2 Aug
from US$91
Tomorrow3 Aug
Mon4 Aug
Tue5 Aug
Wed6 Aug
Thu7 Aug
Fri8 Aug
Sat9 Aug

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 2 August at
    Departure city: Santa Ana
    Departure location: UC Irvine (Crawford Hall)
    Arrival time: 3 August at
    Destination city: Mesa
    Destination location: Mesa Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 2 August at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: 3 August at
    Destination city: Mesa
    Destination location: Mesa Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 August at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: 3 August at
    Destination city: Mesa
    Destination location: Mesa Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 August at
    Departure city: Santa Ana
    Departure location: UC Irvine (Crawford Hall)
    Arrival time: 3 August at
    Destination city: Mesa
    Destination location: Mesa Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 2 August at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: 3 August at
    Destination city: Mesa
    Destination location: Mesa Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Santa Ana, US to Mesa: Trip Overview

Average ticket priceUS$67
Average bus trip duration10h 20m
Number of daily buses4
Earliest bus departure07:45
Distance347 miles
Latest bus departure21:20

Santa Ana to Mesa Bus

With Busbud, comparing and booking tickets for a bus from Santa Ana to Mesa is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santa Ana to Mesa.

From cheap bus tickets to more luxurious buses travelling from Santa Ana to Mesa, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Ana, US - Mesa

  1. What's the distance between Santa Ana and Mesa by coach?

    The distance between Santa Ana and Mesa by coach is approximately 348 miles (561 km).

  2. What is the best way to go from Santa Ana to Mesa without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/07
No data
01/08
No data
Today
US$84
03/08
No data
04/08
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05/08
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06/08
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07/08
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busbud logoThe cheapest trip from Santa Ana, US to Mesa was searched and found on 2 Aug 2025 with a price of US$84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Mesa as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santa Ana to Mesa.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santa Ana to Mesa.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Ana to Mesa that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Ana to Mesa.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Santa Ana, US by bus?

Bus from Santa Ana, US to Mesa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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