Find coaches from St Louis to San Francisco (CA), US

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Today25 May
Tomorrow26 May
from US$368
Tue27 May
Wed28 May
Thu29 May
Fri30 May
Sat31 May
Sun1 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 26 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 28 May at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 26 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 28 May at
    Destination city: San Francisco
    Destination location: San Francisco Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 26 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 28 May at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 28 May at
    Destination city: San Francisco
    Destination location: San Francisco Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 26 May at
    Departure city: St Louis
    Departure location: St Louis, MO
    Arrival time: 28 May at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to travel from St Louis to San Francisco

Average priceUS$141 - US$412Average duration2d 1h
70kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average priceUS$148 - US$1,628Average duration2d 12h
255kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to San Francisco

Among the sustainable travel choices, the bus stands out as a good way to reach San Francisco. The journey takes about 2 days, 1 hour 5 minutes and with fares starting at just US$141, it presents an excellent value for a comfortable ride.

6bus per day
2d 1hAverage duration
US$141Cheapest ticket
70kgCO₂ emissions

Bus St Louis to San Francisco: Trip Overview

Average ticket priceUS$341
Average bus trip duration2d 1h
Number of daily buses6
Earliest bus departure07:35
Distance1736 miles
Latest bus departure16:30

St Louis to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from St Louis to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from St Louis to San Francisco from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from St Louis to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St Louis - San Francisco (CA), US

  1. How much does the St Louis San Francisco coach trip cost?

    The prices typically range from US$141 to US$412 on this trip, with the average ticket costing US$341. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. Use Busbud to compare prices and amenities offered by different companies, ensuring you find the most favorable deals and promotions.

  2. How long is the coach ride from St Louis to San Francisco?

    The coach journey between St Louis and San Francisco lasts about 2d 1h. The fastest coach journey typically takes 1d 21h. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from St Louis to San Francisco?

    The first coach from St Louis to San Francisco leaves at 07:35. Keep in mind that departure times might change on weekends and holidays.

  4. How far is San Francisco from St Louis by coach?

    The journey from St Louis to San Francisco by coach covers an approximate distance of 1740 miles (2806 km).

  5. What is the best way to go from St Louis to San Francisco without flying?

    To travel from St Louis to San Francisco without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

  6. Is there am overnight bus from St Louis to San Francisco?

    Yes, you can find coaches leaving until 16:30 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/05
No data
24/05
No data
Today
No data
26/05
US$362
27/05
No data
28/05
No data
29/05
No data
30/05
No data
busbud logoThe cheapest trip from St Louis to San Francisco was searched and found on 26 May 2025 with a price of US$362

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to San Francisco as early as possible.

You can expect to pay from US$362 to US$372 for a bus ticket from St Louis to San Francisco based on the last 2 days. You can expect to find the cheapest price for the trip at US$362, which is on 2025-05-26.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St Louis to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St Louis to San Francisco, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to San Francisco that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St Louis to San Francisco.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to St Louis by bus?

Bus from St Louis to San Francisco

You can also go to San Francisco by train

Train from St Louis to San Francisco

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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