Next departures to Chicago
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: 10 June atDeparture city: St LouisDeparture location: Gateway StationArrival time: 10 June atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: FlixBus
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: 10 June atDeparture city: St LouisDeparture location: Gateway StationArrival time: 10 June atDestination city: ChicagoDestination location: Chicago 95Th & Dan RyanOperated by: FlixBusVehicle: BusDuration:
- Departure time: 10 June atDeparture city: St LouisDeparture location: Gateway StationArrival time: 11 June atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: Amtrak
Vehicle: BusDuration: - Departure time: 10 June atDeparture city: St LouisDeparture location: Gateway StationArrival time: 10 June atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: 10 June atDeparture city: St LouisDeparture location: Gateway StationArrival time: 10 June atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: FlixBusVehicle: BusDuration:
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Compare 2 ways to travel from St Louis to Chicago
Busbud recommends taking the train from St Louis to ChicagoAmong the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 5 hours 5 minutes and with fares starting at just US$30, it presents an excellent value for a comfortable ride.
Bus St Louis to Chicago: Trip Overview
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St Louis to Chicago Bus
Busbud helps you find a bus from St Louis to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from St Louis to Chicago.
Whether it is cheap bus tickets or more luxurious buses going to Chicago from St Louis, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in St Louis and Chicago?
Frequently asked questions on the trip St Louis - Chicago
How much is the cheapest coach ticket from St Louis to Chicago?
The price for a coach ticket from St Louis to Chicago starts at US$33, though the average is US$51. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. To get accurate and up-to-date pricing information, check out all your options on our search tool.
How long does it take to travel from St Louis to Chicago by bus?
The average duration for a trip from St Louis to Chicago by coach is around 7h. The fastest coach journey typically takes 5h 50m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.
When is the first coach from St Louis to Chicago?
The first departure to Chicago is at 02:30. Keep in mind that departure times might change on weekends and holidays.
How far is Chicago from St Louis by coach?
The distance between St Louis and Chicago by coach is approximately 260 miles (419 km).
Is there a way to reach Chicago from St Louis without flying?
You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St Louis to Chicago was searched and found on 11 Jun 2025 with a price of US$36To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Chicago as early as possible.
You can expect to pay from US$36 to US$228 for a bus ticket from St Louis to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$36, which is on 2025-06-11.
Usually Burlington Trailways, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St Louis and Chicago!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from St Louis to Chicago.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St Louis to Chicago.
Make a music playlist for your bus ride from St Louis to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.