Find coaches from St. Petersburg to Greenville, SC

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Previously seen journeys

One passenger / one way

  • Departure time: 18 September at
    Departure city: St. Petersburg
    Departure location: St Petersburg (Psta Transit Center)
    Arrival time: 19 September at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 18 September at
    Departure city: St. Petersburg
    Departure location: Central Ave N
    Arrival time: 19 September at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 18 September at
    Departure city: St. Petersburg
    Departure location: St Petersburg (Psta Transit Center)
    Arrival time: 19 September at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 18 October at
    Departure city: St. Petersburg
    Departure location: Central Ave N
    Arrival time: 18 October at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: 18 October at
    Departure city: St. Petersburg
    Departure location: St Petersburg (Psta Transit Center)
    Arrival time: 19 October at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus St. Petersburg to Greenville, SC: Trip Overview

Average ticket priceUS$116
Average bus trip duration19h 25m
Number of daily buses3
Earliest bus departure11:40
Distance488 miles
Latest bus departure20:45

St. Petersburg to Greenville Bus

Busbud helps you find a bus from St. Petersburg to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from St. Petersburg to Greenville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from St. Petersburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip St. Petersburg - Greenville, SC

  1. What's the distance between St. Petersburg and Greenville by coach?

    The journey from St. Petersburg to Greenville by coach covers an approximate distance of 483 miles (779 km).

  2. How can I travel from St. Petersburg to Greenville avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
25/08
US$108
26/08
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Today
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28/08
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29/08
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busbud logoThe cheapest trip from St. Petersburg to Greenville, SC was searched and found on 25 Aug 2025 with a price of US$108

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Petersburg to Greenville, SC as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St. Petersburg and Greenville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Petersburg to Greenville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Petersburg to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Petersburg to Greenville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to St. Petersburg by bus?

Bus from Greenville, SC to St. Petersburg

You can also go to Greenville, SC by train

Train from St. Petersburg to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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