Bus Tickets from St. Petersburg to Greenville, SC

Find affordable bus tickets from St. Petersburg to Greenville, SC with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: September 18 at
    Departure city: St. Petersburg
    Departure location: St Petersburg (Psta Transit Center)
    Arrival time: September 19 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 18 at
    Departure city: St. Petersburg
    Departure location: Central Ave N
    Arrival time: September 19 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: September 18 at
    Departure city: St. Petersburg
    Departure location: St Petersburg (Psta Transit Center)
    Arrival time: September 19 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: October 18 at
    Departure city: St. Petersburg
    Departure location: Central Ave N
    Arrival time: October 18 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: October 18 at
    Departure city: St. Petersburg
    Departure location: St Petersburg (Psta Transit Center)
    Arrival time: October 19 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus St. Petersburg to Greenville, SC: Trip Overview

Average Ticket PriceUS$116
Average Bus Trip Duration19h 25m
Number of daily buses3
Earliest bus departure11:40am
Distance786 km
Latest bus departure8:45pm

St. Petersburg to Greenville Bus

Busbud helps you find a bus from St. Petersburg to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from St. Petersburg to Greenville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from St. Petersburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip St. Petersburg - Greenville, SC

  1. How far is St. Petersburg from Greenville?

    The distance between St. Petersburg and Greenville is approximately 779 km (483 miles).

  2. What are the departure and arrival locations for buses traveling from St. Petersburg to Greenville?

    Buses departing from Saint Petersburg Racetrack Bus Stop in St. Petersburg will take you to Guadalajara Supermarket Bus Stop in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-25
US$108
08-26
No data
Today
No data
08-28
No data
08-29
No data
08-30
No data
08-31
No data
09-01
No data
busbud logoThe cheapest trip from St. Petersburg to Greenville, SC was searched and found on Aug 25, 2025 with a price of US$108

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Petersburg to Greenville, SC, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St. Petersburg and Greenville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Petersburg to Greenville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Petersburg to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Petersburg to Greenville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to St. Petersburg by bus?

Bus from Greenville, SC to St. Petersburg

You can also go to Greenville, SC by train

Train from St. Petersburg to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting St. Petersburg

Buses Leaving from St. Petersburg

Buses Going to St. Petersburg

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville