Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train
| Depew Station | Chicago (Union Station), IL | CheapestFastest | ||||
| Train
| Depew Station | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Last Saturday at 16:49 EDT.
Compare 2 ways to travel from Buffalo to Chicago
Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 10 hours 33 minutes and with fares starting at just £55, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Buffalo, NY and Chicago?
Chicago
- A
Union Station
225 S Canal St, Chicago, IL 60606, USA
Train Companies
Based on 6571 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at £55
Frequently asked questions about travelling from Buffalo, NY to Chicago by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Buffalo to Chicago?
The cheapest train tickets from Buffalo to Chicago start from £55. The average price for this train route is around £78. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Buffalo to Chicago?
The average train journey time from Buffalo to Chicago is 10h 33m, covering a distance of 460 miles. The fastest train gets you there in 10h 33m and is operated by Amtrak.
Which train operators serve the Buffalo to Chicago route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to Chicago?
The earliest train from Buffalo to Chicago departs at 00:39. And the latest train departs at 00:39.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Chicago was searched and found on 17 Oct 2026 with a price of £75To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Chicago as early as possible.
You can expect to pay from £75 to £1,124 for a train ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £75, which is on 2026-10-17.
