Next train departures

Next departures for Buffalo to Chicago on August 17
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	CheapestFastest
Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags
Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags

Next departures for Buffalo to Chicago on August 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	CheapestFastest
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags

Next departures for Buffalo to Chicago on August 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	CheapestFastest
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags

Next departures for Buffalo to Chicago on August 20
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	CheapestFastest
Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags
Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags

Next departures for Buffalo to Chicago on August 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	CheapestFastest
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags

Next departures for Buffalo to Chicago on August 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	CheapestFastest
	Train	12:39am	Depew Station	10h 33m	10:12am	Chicago (Union Station), IL	No tags

Last refresh of the prices: Today at 6:27 PM EDT.

Compare 2 ways to go from Buffalo to Chicago

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 10 hours 33 minutes, and with fares starting at just CZK 1,403, it presents an excellent value for a comfortable ride.

1train per day

10h 33mAverage Duration

741 kmDistance

67kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCZK 1,226 - CZK 4,100	Average Duration15h 20m	CO₂ emissions 18kg CO₂e
Train	Average PriceCZK 1,403 - CZK 14,903	Average Duration10h 33m	CO₂ emissions 67kg CO₂e

Where are the popular train stations and stops in Buffalo, NY and Chicago?

Buffalo, NY

A
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Chicago

A
Union Station
225 S Canal St, Chicago, IL 60606, USA

Train companies

Amtrak

4.1/56,429 reviews

Staff4.7

Timeliness3.8

Cleanliness4.5

Wi‑Fi3.6

Based on 6429 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at CZK 1,403

US train companies:Amtrak, Amtrak Acela, Brightline

Frequently asked questions about travelling from Buffalo, NY to Chicago by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Buffalo to Chicago?
The cheapest train tickets from Buffalo to Chicago start at CZK 1,403. The average price for this train route is around CZK 2,491. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Buffalo to Chicago?
The average train trip from Buffalo to Chicago takes 10h 33m and covers 741 km. The quickest train gets you there in 10h 33m and is operated by Amtrak.
Which train operators serve the Buffalo to Chicago route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to Chicago?
The earliest train from Buffalo to Chicago departs at 12:39am. The latest train departs at 12:39am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08-13

CZK 4,270

08-14

CZK 4,270

Today

CZK 4,270

08-16

CZK 4,270

08-17

CZK 4,270

08-18

CZK 3,540

08-19

CZK 3,540

08-20

CZK 3,540

The cheapest trip from Buffalo, NY to Chicago was searched and found on Aug 18, 2026 with a price of CZK 3,540

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Chicago, as early as possible.

You can expect to pay from CZK 3,540 to CZK 31,108 for a train ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 3,540 which is on 2026-08-18.