Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Depew Station | Chicago (Union Station), IL | CheapestFastest | ||||
| Train | Depew Station | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Today at 4:50 AM EDT.
Compare 2 ways to go from Buffalo to Chicago
Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 10 hours 33 minutes, and with fares starting at just COP 253,983, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Buffalo, NY and Chicago?
Chicago
- A
Union Station
225 S Canal St, Chicago, IL 60606, USA
Train companies
Based on 5805 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at COP 253,983
Frequently asked questions about travelling from Buffalo, NY to Chicago by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Buffalo to Chicago?
The cheapest train tickets from Buffalo to Chicago start at COP 253,983. The average price for this train route is around COP 374,603. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Buffalo to Chicago?
The average train trip from Buffalo to Chicago takes 10h 33m and covers 741 km. The quickest train gets you there in 10h 33m and is operated by Amtrak.
Which train operators serve the Buffalo to Chicago route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Buffalo to Chicago?
The earliest train from Buffalo to Chicago departs at 12:39am. The latest train departs at 12:39am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Chicago was searched and found on May 20, 2026 with a price of COP 240,853To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Chicago, as early as possible.
You can expect to pay from COP 240,853 to COP 5,609,524 for a train ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at COP 240,853 which is on 2026-05-20.
