How much does a ticket from Rome to Syracuse cost?

The cheapest tickets from Rome to Syracuse start from CLP 48,076. The average price for this route is around CLP 80,799. Busbud recommends that you book your tickets in advance for a better chance of getting the lowest possible price.

How long is the journey from Rome to Syracuse?

The average trip duration from Rome to Syracuse is 16h 32m, covering a distance of 363 miles. The quickest vehicle can get you there in 11h 5m and is operated by Trenitalia .

Which companies operate the Rome to Syracuse route?

Several major companies operate on this route with 2 trips available per day, including services from FlixBus , Trenitalia .

What are the earliest and latest departure times from Rome to Syracuse?

The earliest service departs from Rome for Syracuse at 07:26. And the latest service departs at 23:55.

What are the CO₂ emissions for the journey from Rome to Syracuse?

A journey from Rome to Syracuse produces an estimated 14.6360375 kg of CO₂, making it a highly eco-friendly way to travel and a mode of transport recommended by Busbud.

Which is the best company from Rome to Syracuse?

According to Busbud customers, the highest-rated company on this route is Trenitalia , with an average rating of 3.9 out of 5 stars based on 58 reviews.

Which company has the best Wi-Fi from Rome to Syracuse?

According to reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which company offers the most punctual service from Rome to Syracuse?

According to Busbud traveller reviews, the most punctual company on this route is Trenitalia , with a punctuality rating of 4.6 out of 5 stars.

Which company has the cleanest vehicles from Rome to Syracuse?

According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia , with a cleanliness rating of 4.7 out of 5 stars.

Bus and Train Rome to Syracuse from CLP 46,126 | Refundable Tickets

Next available departures

Next departures from Rome to Syracuse on 20 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
22:35	Rome Fiumicino Airport	22h 5m	20:40	Terminal Interbus	Cheapest
07:26	Termini	11h 5m	18:31	Syracuse	Fastest
21:00	Rome Tiburtina Bus Station	12h 15m	09:15	Terminal Interbus	No tags
22:40	Aeroporto Ciampino Airport (CIA)	22h	20:40	Terminal Interbus	No tags

Last refresh of the prices: Yesterday at 21:30 CEST.

Compare 2 ways to travel from Rome to Syracuse

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 11 hours 5 minutes and with fares starting at just CLP 51,616, it presents an excellent value for a comfortable ride.

1train per day

11h 5mAverage duration

365 milesDistance

14kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceCLP 48,076 - CLP 144,191	Average duration22h	CO₂ emissions 15kg CO₂e
Train	Average priceCLP 51,616 - CLP 124,592	Average duration11h 5m	CO₂ emissions 14kg CO₂e

Where are the popular stops in Rome and Syracuse?

Stops in Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
Visit page
D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
Visit page
E
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Visit page
F
Cesano di Roma
Cesano Di Roma, 00123 Roma RM, Italy
Visit page

Stops in Syracuse

A
S. Teresa Longarini
Via Elorina, 129, 96100 Siracusa SR, Italy
B
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy
Visit page
C
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy
D
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy

Compare companies

FlixBus

3.5/512,502 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Trenitalia

3.9/558 reviews

Staff4.6

Timeliness4.6

Cleanliness4.7

Wi‑Fi2.5

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn ICE, ALSA, RegioJet, Rede Expressos, Deutsche Bahn, Trenitalia, FlixTrain, Sindbad, Italo, MarinoBus, Swiss Federal Railways

Frequently asked questions about travelling from Rome to Syracuse by bus or train

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much does a ticket from Rome to Syracuse cost?
The cheapest tickets from Rome to Syracuse start from CLP 48,076. The average price for this route is around CLP 80,799. Busbud recommends that you book your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Rome to Syracuse?
The average trip duration from Rome to Syracuse is 16h 32m, covering a distance of 363 miles. The quickest vehicle can get you there in 11h 5m and is operated by Trenitalia.
Which companies operate the Rome to Syracuse route?
Several major companies operate on this route with 2 trips available per day, including services from FlixBus, Trenitalia.
What are the earliest and latest departure times from Rome to Syracuse?
The earliest service departs from Rome for Syracuse at 07:26. And the latest service departs at 23:55.
What are the CO₂ emissions for the journey from Rome to Syracuse?
A journey from Rome to Syracuse produces an estimated 14.6360375 kg of CO₂, making it a highly eco-friendly way to travel and a mode of transport recommended by Busbud.
Which is the best company from Rome to Syracuse?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 58 reviews.
Which company has the best Wi-Fi from Rome to Syracuse?
According to reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which company offers the most punctual service from Rome to Syracuse?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Rome to Syracuse?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

17/04

CLP 48,867

18/04

CLP 102,963

Today

CLP 51,967

20/04

CLP 62,849

21/04

CLP 46,126

22/04

CLP 55,660

23/04

CLP 61,178

24/04

CLP 56,972

The cheapest trip from Rome to Syracuse was searched and found on 21 Apr 2026 with a price of CLP 46,126

To save money and ensure you get the best seat, it's a good idea to buy your bus and train tickets from Rome to Syracuse, as early as possible.

You can expect to pay between CLP 46,126 and CLP 119,605 for a bus or train ticket from Rome to Syracuse based on the past 2 days. You can expect to find the lowest price for the trip at CLP 46,126 on 2026-04-21.

Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.