Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | BILOXI | Downtown Transit Center | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | BILOXI | Downtown Transit Center | Fastest | ||||
 | Bus | BILOXI | Indianapolis Bus Station | No tags | ||||
| Bus | BILOXI | Indianapolis Bus Station | No tags |
Last refresh of the prices: Last Sunday at 2:01 AM CST.
Get from Biloxi to Indianapolis
The journey takes about 23 hours and with fares starting at just $107, it presents an excellent value for a comfortable ride.
Where are the popular stops in Biloxi and Indianapolis?
Stops in Biloxi
- A11332 Cedar Lake Rd, Biloxi, MS 39532, USA
- B
Transit Center
820 Dr Martin Luther King Jr Blvd, Biloxi, MS 39530, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Biloxi to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Biloxi to Indianapolis?
The cheapest bus tickets from Biloxi to Indianapolis start from $107. The average price for this route is around $138. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Biloxi to Indianapolis?
The average bus trip duration from Biloxi to Indianapolis is 23h, covering a distance of 664 miles (1071 km). The quickest bus can get you there in 23h and is operated by Greyhound.
Which bus companies service the Biloxi to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Biloxi to Indianapolis?
The earliest bus departs from Biloxi to Indianapolis at 9:55am. And the latest bus departs at 3:05pm.
What are the CO₂ emissions for the bus trip from Biloxi to Indianapolis?
A bus trip from Biloxi to Indianapolis generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Biloxi to Indianapolis was searched and found on Feb 19, 2026 with a price of $116To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Biloxi to Indianapolis, as early as possible.
You can expect to pay from $116 to $220 for a bus ticket from Biloxi to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $130 which is on 2026-02-22.
