Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Calexico to Houston, US by bus
What is the distance between Calexico and Houston?
About 1206 miles (1944 km) separate Calexico and Houston.
What are the departure and arrival stations when taking the bus from Calexico to Houston?
If you're headed to Houston from Calexico, chances are that your bus will leave from Calexico Bus Station and arrive at Hillcroft Ave & Southwest Freeway. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Houston?
Once in Houston, you can start exploring the city and discover its surroundings. The top sights and things to do are iFLY Indoor Skydiving, Galveston, NASA Johnson Space Center, Hermann Park Conservancy and City Hall.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
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Today
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11/22
$218
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The cheapest trip from Calexico to Houston, US was searched and found on Nov 22, 2025 with a price of $218
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calexico to Houston, US, as early as possible.
You can expect to pay from $218 to $218 for a bus ticket from Calexico to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $218 which is on 2025-11-22.