Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | No tags | ||||
 | Bus | Downtown Greyhound Station | Midway Truck Plaza Bus Stop | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Columbia Wabash Station | No tags |
Last refresh of the prices: Today at 1:11 PM CDT.
Get from Chicago to Columbia
The journey takes about 15 hours 5 minutes and with fares starting at just COP 218,358, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Columbia?
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Chicago to Columbia, MO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Columbia?
The cheapest bus tickets from Chicago to Columbia start from COP 218,358. The average price for this route is around COP 296,930. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Columbia?
The average bus trip duration from Chicago to Columbia is 15h 5m, covering a distance of 318 miles (512 km). The quickest bus can get you there in 14h 45m and is operated by Greyhound.
Which bus companies service the Chicago to Columbia route?
Several major bus companies operate on this route with 18 buses available per day.
What is the earliest and latest departure time for the bus from Chicago to Columbia?
The earliest bus departs from Chicago to Columbia at 12:15am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Chicago to Columbia?
A bus trip from Chicago to Columbia generates an estimated 12.7935 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Columbia, MO was searched and found on Jun 17, 2026 with a price of COP 219,537To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Columbia, MO, as early as possible.
You can expect to pay from COP 219,537 to COP 626,680 for a bus ticket from Chicago to Columbia, MO based on the last 2 days. You can expect to find the cheapest price for the trip at COP 219,537 which is on 2026-06-17.
