Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Chicago 95Th & Dan Ryan | Salisbury (Citgo Fast Stop) | Cheapest | ||||
| Bus | Downtown Greyhound Station | Salisbury (Citgo Fast Stop) | Fastest | ||||
| Bus | 537-517 W. Jackson Blvd | Salisbury (Citgo Fast Stop) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | 537-517 W. Jackson Blvd | Salisbury (Citgo Fast Stop) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Salisbury (Citgo Fast Stop) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Salisbury (Citgo Fast Stop) | No tags |
Last refresh of the prices: Yesterday at 12:39 AM CDT.
Compare 2 ways to go from Chicago to Salisbury
Among the sustainable travel choices, the Bus stands out as a good way to reach Salisbury. The journey takes about 23 hours 40 minutes and with fares starting at just PEN 326, it presents an excellent value for a comfortable ride.
Bus stations and stops in Chicago and Salisbury
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Chicago to Salisbury, NC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Salisbury?
The cheapest bus tickets from Chicago to Salisbury start from PEN 326. The average price for this route is around PEN 451. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Salisbury?
The average bus trip duration from Chicago to Salisbury is 23h 40m, covering a distance of 573 miles (924 km). The quickest bus can get you there in 19h 10m and is operated by Greyhound.
Which bus companies service the Chicago to Salisbury route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Chicago to Salisbury?
The earliest bus departs from Chicago to Salisbury at 4:45am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Chicago to Salisbury?
A bus trip from Chicago to Salisbury generates an estimated 23.077375 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Salisbury, NC, US was searched and found on Aug 13, 2026 with a price of PEN 321To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Salisbury, NC, US, as early as possible.
You can expect to pay from PEN 321 to PEN 661 for a bus ticket from Chicago to Salisbury, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at PEN 321 which is on 2026-08-13.
What's the cheapest way to go from Chicago to Salisbury, NC, US?
The Bus is the cheapest travel choice for this destination
