Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Chicago (Bus Station) | MLK Transportation Center | CheapestFastest |
Last refresh of the prices: Last Friday at 10:54 PM CST.
Get from Chicago to Sioux City
The journey takes about 10 hours 35 minutes and with fares starting at just $173, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Sioux City?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Sioux City
- A
W Maple St
4110 W Maple St, Sioux Falls, SD 57107, USA
Compare bus companies
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Frequently asked questions about traveling from Chicago to Sioux City by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Sioux City?
The cheapest bus tickets from Chicago to Sioux City start from $173. The average price for this route is around $190. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Sioux City?
The average bus trip duration from Chicago to Sioux City is 10h 35m, covering a distance of 450 miles (725 km). The quickest bus can get you there in 10h 35m and is operated by Jefferson Lines.
Which bus companies service the Chicago to Sioux City route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Chicago to Sioux City?
The earliest bus departs from Chicago to Sioux City at 9:15pm. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from Chicago to Sioux City?
A bus trip from Chicago to Sioux City generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Sioux City was searched and found on Jan 7, 2026 with a price of $168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Sioux City, as early as possible.
You can expect to pay from $168 to $188 for a bus ticket from Chicago to Sioux City based on the last 2 days. You can expect to find the cheapest price for the trip at $168 which is on 2026-01-09.
