Bus Tickets from Cleveland, OH, US to St Louis

Find affordable bus tickets from Cleveland, OH, US to St Louis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 13
TomorrowJul 14
TueJul 15
from $88
WedJul 16
from $86
ThuJul 17
from $89
FriJul 18
from $93
SatJul 19
from $104
SunJul 20
from $99

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 15 at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: July 15 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 15 at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: July 16 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: July 16 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Cleveland to St Louis.

Bus
Average Price$71 - $183Average Duration16h 5m
20kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$80 - $861Average Duration20h 24m
72kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Cleveland to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 16 hours 5 minutes and with fares starting at just $71, it presents an excellent value for a comfortable ride.

1bus per day
16h 5mAverage Duration
$71Cheapest ticket
20kgCO₂ emissions

Bus Cleveland to St. Louis: Trip Overview

Average ticket price$92
Average bus trip duration16h 5m
Number of daily buses1
Earliest bus departure8:00am
Distance492 miles (792 km)
Latest bus departure5:20pm

Cleveland to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Cleveland to St Louis.

We make it our job to connect you with the most dependable bus companies that cover bus service from Cleveland to St Louis.

From cheap bus tickets to more luxurious buses traveling from Cleveland to St Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Cleveland, OH, US - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/11
No data
07/12
No data
Today
$138
07/14
$74
07/15
$80
07/16
$85
07/17
$83
07/18
$86
busbud logoThe cheapest trip from Cleveland to St. Louis was searched and found on Jul 14, 2025 with a price of $74

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cleveland to St. Louis, as early as possible.

You can expect to pay from $74 to $138 for a bus ticket from Cleveland to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-07-14.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Cleveland to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Cleveland to St Louis.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Cleveland to St Louis that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Cleveland to St Louis.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Cleveland to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Cleveland by bus?

Bus from Cleveland to St. Louis

You can also go to St Louis by train

Train from Cleveland, OH, US to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Cleveland

Buses Leaving from Cleveland

Buses Going to Cleveland

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis