Bus Des Moines to Sioux Falls: Trip Overview
Compare bus companies
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Des Moines to Sioux Falls Bus
With Busbud, comparing and booking tickets for a bus from Des Moines to Sioux Falls is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Des Moines to Sioux Falls will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Sioux Falls from Des Moines, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Des Moines and Sioux Falls?
Frequently asked questions for your trip Des Moines - Sioux Falls
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Sioux Falls was searched and found on Jun 12, 2025 with a price of $168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Sioux Falls, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Des Moines to Sioux Falls.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Des Moines to Sioux Falls, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Sioux Falls.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Des Moines to Sioux Falls.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Des Moines
Buses Leaving from Des Moines
- Bus from Des Moines to Iowa City
- Bus Des Moines - Washington
- Des Moines - Omaha
- Bus from Des Moines to Denver
- Bus Des Moines - Cedar Rapids
- Des Moines - Chicago
- Bus from Des Moines to Minneapolis
- Bus Des Moines - Kansas City
- Des Moines - Sioux Falls
- Bus from Des Moines to Madison
- Bus Des Moines - Ames
- Des Moines - Dallas
- Bus from Des Moines to Davenport
- Bus Des Moines - Los Angeles
- Des Moines - Worthington
Buses Going to Des Moines
- Bus from Washington to Des Moines
- Bus Chicago - Des Moines
- Minneapolis - Des Moines
- Bus from Las Vegas to Des Moines
- Bus Staples - Des Moines
- Iowa City - Des Moines
- Bus from Ames to Des Moines
- Bus Kansas City - Des Moines
- Sioux City - Des Moines
- Bus from Denver to Des Moines
- Bus Dallas - Des Moines
- St Louis - Des Moines
- Bus from Greenfield to Des Moines
- Bus Omaha - Des Moines
- New York - Des Moines
Popular Buses Connecting Sioux Falls
Buses Leaving from Sioux Falls
- Bus from Sioux Falls to Rapid City
- Bus Sioux Falls - Fargo
- Sioux Falls - Minneapolis
- Bus from Sioux Falls to Omaha
- Bus Sioux Falls - Sioux City
- Sioux Falls - Kansas City
- Bus from Sioux Falls to Watertown
- Bus Sioux Falls - Pierre
- Sioux Falls - Brookings
- Bus from Sioux Falls to Vermillion
- Bus Sioux Falls - Des Moines
- Sioux Falls - Duluth
- Bus from Sioux Falls to Worthington
- Bus Sioux Falls - Huron
- Sioux Falls - Fort Dodge
Buses Going to Sioux Falls
- Bus from Minneapolis to Sioux Falls
- Bus Fargo - Sioux Falls
- Rapid City - Sioux Falls
- Bus from Brookings to Sioux Falls
- Bus Vermillion - Sioux Falls
- Aberdeen - Sioux Falls
- Bus from Omaha to Sioux Falls
- Bus Des Moines - Sioux Falls
- Watertown - Sioux Falls
- Bus from Worthington to Sioux Falls
- Bus Pierre - Sioux Falls
- Kansas City - Sioux Falls
- Bus from Mitchell to Sioux Falls
- Bus Fairmont - Sioux Falls
- Marshall - Sioux Falls