Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Minneapolis (U of MN - Huron Blvd) | Sioux Falls | Cheapest | ||||
| Bus | Minneapolis | Sioux Falls | Fastest | ||||
| Bus | Minneapolis | Sioux Falls | No tags | ||||
| Bus | MSP Airport T1 (Minneapolis International Airport) | Sioux Falls | No tags |
Last refresh of the prices: Last Wednesday at 8:47 PM CST.
Get from Minneapolis to Sioux Falls
The journey takes about 7 hours 55 minutes and with fares starting at just $70, it presents an excellent value for a comfortable ride.
Where are the popular stops in Minneapolis and Sioux Falls?
Stops in Minneapolis
- A
Greyhound Station
950 Hawthorne Ave, Minneapolis, MN 55403, USA - B
MSP Airport
Ground Transportation Center, Terminal 1, 6498 34th Ave S, St Paul, MN 55111, USA
Stops in Sioux Falls
- A
Jefferson Lines Station I-29 & Maple St
4101 W Maple St, Sioux Falls, SD 57107, USA
Compare bus companies
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Jefferson Lines Minneapolis Sioux Falls recent customer reviews
I was at the appropriate bus pick up location and no bus showed up. I had to take the metro to the Jefferson/Greyhound station to get on a bus. There was also little to no information about Jefferson at the MSP airport. Overall, very dissatisfied and upset.
Samuel S.
Got the impression that this was the first time this driver had done this route - she got lost twice. Not her fault, Jefferson should be training staff properly and getting new drivers to shadow routes before driving them, or have an experienced driver with them the first few times they do a new route.
Tim G.
I missed my bus and can’t change the bus ticket. I’m stuck at the airport.
Randy K.
Frequently asked questions about traveling from Minneapolis to Sioux Falls by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Minneapolis to Sioux Falls was searched and found on Nov 25, 2025 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Minneapolis to Sioux Falls, as early as possible.
You can expect to pay from $68 to $185 for a bus ticket from Minneapolis to Sioux Falls based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2025-11-25.
Top traveled bus routes
People from around the world trust Busbud
Popular bus departures from Minneapolis
- Find bus tickets from Minneapolis to Wausau
- Minneapolis to Duluth bus times and fares
- How to travel from Minneapolis to Chicago
- Find bus tickets from Minneapolis to Madison
- Minneapolis to Milwaukee bus times and fares
- How to travel from Minneapolis to Green Bay
- Find bus tickets from Minneapolis to New York City