Bus Tickets from Detroit (MI) to Charleston (SC), US

Find affordable bus tickets from Detroit (MI) to Charleston (SC), US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TueJun 3
from $391
WedJun 4
ThuJun 5
FriJun 6
SatJun 7
SunJun 8
MonJun 9
TueJun 10

Next departures to Charleston

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 3 at
    Departure city: Detroit
    Departure location: Amtrak Station
    Arrival time: June 5 at
    Destination city: Charleston
    Destination location: Charleston Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: June 3 at
    Departure city: Detroit
    Departure location: Amtrak Station
    Arrival time: June 5 at
    Destination city: Charleston
    Destination location: Charleston Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Detroit to Charleston.

Bus
Average Price$167 - $167Average Duration1d 6h
27kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$340 - $420Average Duration1d 19h
99kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Detroit to Charleston

Among the sustainable travel choices, the bus stands out as the good way to reach Charleston. The journey takes about 1 day, 6 hours 50 minutes and with fares starting at just $167, it presents an excellent value for a comfortable ride.

1bus per day
1d 6hAverage Duration
$167Cheapest ticket
27kgCO₂ emissions

Bus Detroit to Charleston: Trip Overview

Average ticket price$167
Average bus trip duration1d 6h
Number of daily buses1
Earliest bus departure7:00am
Distance673 miles (1085 km)

Detroit to Charleston Bus

Busbud helps you find a bus from Detroit to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Detroit to Charleston from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Detroit to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Detroit (MI) - Charleston (SC), US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/30
No data
05/31
No data
Today
No data
06/02
No data
06/03
$376
06/04
No data
06/05
No data
06/06
No data
busbud logoThe cheapest trip from Detroit to Charleston was searched and found on Jun 3, 2025 with a price of $376

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to Charleston, as early as possible.

You can expect to pay from $376 to $1,332 for a bus ticket from Detroit to Charleston based on the last 2 days. You can expect to find the cheapest price for the trip at $376 which is on 2025-06-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Detroit and Charleston!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Charleston, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Charleston that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Detroit to Charleston.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Detroit to Charleston?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Detroit by bus?

Bus from Detroit to Charleston

You can also go to Charleston by train

Train from Detroit to Charleston

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Detroit

Buses Leaving from Detroit

Buses Going to Detroit

Popular Buses Connecting Charleston

Buses Leaving from Charleston

Buses Going to Charleston