Bus from Durham, NC, US to Syracuse, US: Tickets & Schedules

Next bus departures

Next departures for Durham to Syracuse on March 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Durham Greyhound Bus Station
Syracuse (Regional Transportation Center)CheapestFastest
Greyhound Lines, Inc.Bus
Durham Greyhound Bus Station
Syracuse (Regional Transportation Center)No tags

Last refresh of the prices: Yesterday at 6:56 PM EST.

Compare 2 ways to go from Durham to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 18 hours 15 minutes and with fares starting at just $114, it presents an excellent value for a comfortable ride.

3bus per day
18h 15mAverage Duration
510 milesDistance
21kgCO₂ emissions
Average Price$114 - $298Average Duration18h 15m
21kg CO₂e
Average Price$154 - $354Average Duration1d 3h
75kg CO₂e

Frequently asked questions about traveling from Durham, NC, US to Syracuse, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Durham to Syracuse?

    The cheapest bus tickets from Durham to Syracuse start from $114. The average price for this route is around $188. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Durham to Syracuse?

    The average bus trip duration from Durham to Syracuse is 18h 15m, covering a distance of 510 miles (822 km). The quickest bus can get you there in 17h 40m and is operated by FlixBus.

  3. Which bus companies service the Durham to Syracuse route?

    Several major bus companies operate on this route with 3 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Durham to Syracuse?

    The earliest bus departs from Durham to Syracuse at 2:40am. And the latest bus departs at 9:15pm.

  5. What are the CO₂ emissions for the bus trip from Durham to Syracuse?

    A bus trip from Durham to Syracuse generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Durham to Syracuse?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12256 reviews.

  7. Which bus company has the best Wi-Fi from Durham to Syracuse?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Durham to Syracuse?

    According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Durham to Syracuse?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/01
$236
03/02
$106
Today
$180
03/04
No data
03/05
No data
03/06
No data
03/07
No data
03/08
No data
busbud logoThe cheapest trip from Durham, NC, US to Syracuse, US was searched and found on Mar 2, 2026 with a price of $106

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Syracuse, US, as early as possible.

What's the cheapest way to go from Durham, NC, US to Syracuse, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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