What is the travel distance from Durham to Syracuse?

About 509 miles (820 km) separate Durham and Syracuse.

What are the departure and arrival stations when taking the bus from Durham to Syracuse?

The majority of buses traveling from Durham to Syracuse start their journey at Durham Greyhound Bus Station and wind up at Regional Transportation Center. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Everson Museum of Art, Rosamond Gifford Zoo, MOST, Onondaga Lake Park and The Great New York State Fair.

Bus Durham to Syracuse from $81 | Refundable Tickets

Next departures

Next departures for Durham to Syracuse on November 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.		9:15pm	Durham Greyhound Bus Station	18h	3:15pm	Syracuse (Regional Transportation Center)	CheapestFastest

Next departures for Durham to Syracuse on November 8
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:45am	Durham Greyhound Bus Station	17h 45m	9:30pm	Syracuse (Regional Transportation Center)	Cheapest
FlixBus + Greyhound Lines, Inc.	2:40am	Durham Greyhound Bus Station	16h 50m	7:30pm	Syracuse (Regional Transportation Center)	Fastest
	9:10am	Durham Greyhound Bus Station	18h 45m	3:55am	Syracuse (Regional Transportation Center)	No tags
FlixBus + Greyhound Lines, Inc.	5:05pm	Durham Greyhound Bus Station	18h 15m	11:20am	Syracuse (Regional Transportation Center)	No tags
FlixBus + Greyhound Lines, Inc.	9:15pm	Durham Greyhound Bus Station	18h	3:15pm	Syracuse (Regional Transportation Center)	No tags

Next departures for Durham to Syracuse on November 9
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	9:15pm	Durham Greyhound Bus Station	18h	3:15pm	Syracuse (Regional Transportation Center)	Cheapest
	3:45am	Durham Greyhound Bus Station	17h 45m	9:30pm	Syracuse (Regional Transportation Center)	Fastest
	9:10am	Durham Greyhound Bus Station	18h 45m	3:55am	Syracuse (Regional Transportation Center)	No tags
FlixBus + Greyhound Lines, Inc.	5:05pm	Durham Greyhound Bus Station	18h 15m	11:20am	Syracuse (Regional Transportation Center)	No tags

Last refresh of the prices: Last Tuesday at 7:05 PM EST.

Compare 2 ways to go from Durham to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 18 hours and with fares starting at just $114, it presents an excellent value for a comfortable ride.

4bus per day

18hAverage Duration

510 milesDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$114 - $288	Average Duration18h	CO₂ emissions 21kg CO₂e
Train	Average Price$257 - $377	Average Duration1d 3h	CO₂ emissions 75kg CO₂e

Bus Durham, NC, US to Syracuse, US: Trip Overview

Average ticket price$198

Average bus trip duration18h

Number of daily buses4

Earliest bus departure1:20am

Distance510 miles (821 km)

Latest bus departure9:15pm

Compare bus companies

FlixBus

3.5/511,204 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,354 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Durham to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Durham to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Durham to Syracuse will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Syracuse from Durham, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Durham and Syracuse?

Stops in Durham

A - Durham Greyhound Bus Station

B - Compare Foods Durham

C - Durham Compare Foods Durham

D - Durham, NC

Stops in Syracuse

A - Regional Transportation Center

B - Syracuse Airport

C - Syracuse University

D - Syracuse University - Lyman Hall

E - New York State Fairgrounds

F - Syracuse, NY

Frequently asked questions for your trip Durham, NC, US - Syracuse, US

What is the travel distance from Durham to Syracuse?
What are the departure and arrival stations when taking the bus from Durham to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/04

No data

11/05

$187

Today

$151

11/07

No data

11/08

$81

11/09

$114

11/10

No data

11/11

No data

The cheapest trip from Durham, NC, US to Syracuse, US was searched and found on Nov 8, 2025 with a price of $81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Syracuse, US, as early as possible.

You can expect to pay from $81 to $187 for a bus ticket from Durham, NC, US to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $81 which is on 2025-11-08.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Durham to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Durham to Syracuse, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Syracuse.

Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Syracuse while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Durham, NC, US to Syracuse, US?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time18h	Avg Price$198	Daily Departures4
Vehicle TypeTrain	Travel Time1d 3h	Avg Price$314	Daily Departures1

Will you be returning to Durham, NC, US by bus?

Bus from Syracuse, US to Durham, NC, US

You can also go to Syracuse, US by train

Train from Durham, NC, US to Syracuse, US

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.