Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Buffalo (BUF) Airport | Amtrak Station | Cheapest | ||||
 | Bus | Niagara Frontier Transportation Authority | Syracuse (Regional Transportation Center) | Fastest | ||||
 | Bus | Niagara Frontier Transportation Authority | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Transportation Center | Amtrak Station | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Transportation Center | Amtrak Station | No tags |
Last refresh of the prices: Yesterday at 9:51 PM EDT.
Compare 2 ways to go from Buffalo to Syracuse
Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 2 hours 23 minutes and with fares starting at just NZ$52, it presents an excellent value for a comfortable ride.
Bus stations and stops in Buffalo and Syracuse
Stops in Buffalo
- B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA - C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Stops in Syracuse
- B
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210 - D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
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Frequently asked questions about traveling from Buffalo, NY to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Syracuse?
The cheapest bus tickets from Buffalo to Syracuse start from NZ$50. The average price for this route is around NZ$57. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Syracuse?
The average bus trip duration from Buffalo to Syracuse is 3h 5m, covering a distance of 135 miles (217 km). The quickest bus can get you there in 2h 25m and is operated by Greyhound.
Which bus companies service the Buffalo to Syracuse route?
Several major bus companies operate on this route with 31 buses available per day, including services from FlixBus, Adirondack Trailways, Greyhound, OurBus, New York Trailways.
What is the earliest and latest departure time for the bus from Buffalo to Syracuse?
The earliest bus departs from Buffalo to Syracuse at 12:20am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Syracuse?
A bus trip from Buffalo to Syracuse generates an estimated 5.409800000000001 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Buffalo to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways, with an average rating of 4.1 out of 5 stars based on 1167 reviews.
Which bus company has the best Wi-Fi from Buffalo to Syracuse?
Based on reviews on Busbud, the bus company New York Trailways has the best Wi-Fi rating with a score of 3.1.
Which bus company has the most timely service from Buffalo to Syracuse?
According to Busbud traveler reviews, the most timely bus company on this route is Adirondack Trailways, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Syracuse?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Adirondack Trailways, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Syracuse, US was searched and found on Jul 29, 2026 with a price of NZ$36To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Syracuse, US, as early as possible.
You can expect to pay from NZ$36 to NZ$229 for a bus ticket from Buffalo, NY to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at NZ$36 which is on 2026-07-29.
Usually Adirondack Trailways will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Buffalo, NY to Syracuse, US?
The Bus is the cheapest travel choice for this destination
