Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Erie Bus Station | Gateway Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Erie Bus Station | Gateway Station | No tags |
Last refresh of the prices: Today at 1:14 AM EST.
Compare 2 ways to go from Erie to St. Louis
Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 20 hours 15 minutes and with fares starting at just $81, it presents an excellent value for a comfortable ride.
Where are the popular stops in Erie and St. Louis?
Stops in Erie
- A
Erie Bus Station
208 E Bayfront Pkwy, Erie, PA 16507
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Frequently asked questions about traveling from Erie to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Erie to St. Louis?
The cheapest bus tickets from Erie to St. Louis start from $81. The average price for this route is around $149. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Erie to St. Louis?
The average bus trip duration from Erie to St. Louis is 20h 15m, covering a distance of 584 miles (942 km). The quickest bus can get you there in 20h 15m and is operated by Greyhound.
Which bus companies service the Erie to St. Louis route?
What is the earliest and latest departure time for the bus from Erie to St. Louis?
The earliest bus departs from Erie to St. Louis at 9:50am. And the latest bus departs at 12:40pm.
What are the CO₂ emissions for the bus trip from Erie to St. Louis?
A bus trip from Erie to St. Louis generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Erie to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Erie to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Erie to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Erie to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Erie to St. Louis was searched and found on Jan 7, 2026 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Erie to St. Louis, as early as possible.
You can expect to pay from $121 to $168 for a bus ticket from Erie to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2026-01-07.
What's the cheapest way to go from Erie to St. Louis?
The Bus is the cheapest travel choice for this destination
