Next departures for Erie to Syracuse on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Erie Bus Station
Syracuse (Regional Transportation Center)
CheapestFastest
Last refresh of the prices: Today at 5:30 PM EST.
Compare 2 ways to go from Erie to Syracuse
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Syracuse. The journey takes about 4 hours 4 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
D - Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E - New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F - Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Frequently asked questions about traveling from Erie to Syracuse, US by bus
How far is Erie from Syracuse?
The distance separating Erie and Syracuse is 210 miles (339 km).
What are the departure and arrival stations when taking the bus from Erie to Syracuse?
Most of the buses traveling from Erie to Syracuse leave from Erie Bus Station and arrive at Regional Transportation Center. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Syracuse?
Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Carrier Dome, NBT Bank Stadium, Onondaga Historical Association Museum, MOST and Rosamond Gifford Zoo.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$49
11/18
$46
Today
$49
11/20
$53
11/21
$57
11/22
$58
11/23
$72
11/24
$62
The cheapest trip from Erie to Syracuse, US was searched and found on Nov 18, 2025 with a price of $46
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Erie to Syracuse, US, as early as possible.
You can expect to pay from $46 to $72 for a bus ticket from Erie to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-11-20.
The cheapest trip from Erie to Syracuse, US was searched and found on Nov 18, 2025 with a price of $46
