Next departures for Florence to Charleston on November 23
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Bus station
4565 Gaynor Ave, North Charleston
CheapestFastest
Next departures for Florence to Charleston on November 24
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Bus station
4565 Gaynor Ave, North Charleston
CheapestFastest
Next departures for Florence to Charleston on November 25
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Bus station
4565 Gaynor Ave, North Charleston
CheapestFastest
Next departures for Florence to Charleston on November 26
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Bus station
4565 Gaynor Ave, North Charleston
CheapestFastest
Next departures for Florence to Charleston on November 27
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Bus station
4565 Gaynor Ave, North Charleston
CheapestFastest
Last refresh of the prices: Today at 10:24 AM EST.
Compare 2 ways to go from Florence to Charleston
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 1 hour 33 minutes and with fares starting at just $18, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Florence, SC, US to Charleston, SC, US by bus
How far is Florence from Charleston?
About 100 miles (162 km) separate Florence and Charleston.
What are the departure and arrival stations when taking the bus from Florence to Charleston?
Most of the buses traveling from Florence to Charleston leave from Florence Bus Station and arrive at Charleston Bus Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Charleston?
Once in Charleston, you can start exploring the city and discover its surroundings. The top sights and things to do are Charleston Ghost and Dungeon Tour, On Purpose Adventures, Dock Street Theatre, Charleston Food Tours and Theatre 99.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/20
$31
11/21
$36
Today
$35
11/23
$39
11/24
$33
11/25
$35
11/26
$42
11/27
$34
The cheapest trip from Florence, SC, US to Charleston, SC, US was searched and found on Nov 20, 2025 with a price of $31
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Charleston, SC, US, as early as possible.
You can expect to pay from $31 to $42 for a bus ticket from Florence, SC, US to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $33 which is on 2025-11-24.
What's the cheapest way to go from Florence, SC, US to Charleston, SC, US?
The bus is the cheapest travel choice for this destination