Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Autobuses de Tlaquepaque | Mezcales Central Bus Station | Cheapest | ||||
 | Bus | Central Camionera Poniente | Nuevo Vallarta, Nayarit | Fastest | ||||
| Bus | Central Camionera Poniente | Nuevo Vallarta, Nayarit | No tags | ||||
| Bus | Zapopan Guadalajara | Mezcales Central Bus Station | No tags | ||||
 | Bus | Estación Juárez Parada de Autobuses | Nogales Av. Alvaro Obregon | No tags |
Last refresh of the prices: Yesterday at 10:44 PM CST.
Compare 2 ways to go from Guadalajara to Mezcales
Among the sustainable travel choices, the Carpool stands out as a good way to reach Mezcales. The journey takes about 3 hours 40 minutes and with fares starting at just $9, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$47 - $165 | Average Duration4h 30m | 5kg CO₂e | ||
Carpool | Average Price$9 - $24 | Average Duration3h 40m | 9kg CO₂e |
Where are the popular stops in Guadalajara and Mezcales?
Stops in Guadalajara
- A
Estación Juárez Parada de Autobuses
Av. Del Federalismo Nte. 800 (esq. Av. Juárez), 44100 Guadalajara, Jalisco, Mexico - B
Terminal de Autobuses de Tlaquepaque
Anillo Periférico Sur #8010, Col. Santa María Tequepexpan, 45601 Tlaquepaque, Jalisco - C
Nueva Central Guadalajara (Tlaquepaque)
Terminal de Autobuses de Guadalajara, Carretera Libre a Zapotlanejo y entronque carretera a Tonalá Km. 1.5, 44100 Guadalajara - D
Guadalajara Airport
- E
Terminal de Autobuses Nuevo Milenio de Zapopan
Carretera A Nogales No. 1110, Casi Esq. Av. Aviación (Col. San Juan de Ocotan), 20230 Zapopan, Jal. - F
Forum de Tlaquepaque - Parada de Autobuses
Blvd. Marcelino García Barragán No. 2077 (Col. Lomas del Paradero), 44840, Guadalajara
Stops in Mezcales
- A
Parada de Autobuses de Mezcales
Carretera Vallarta-Tepic # 210 , Colonia Ica, Menchaca, 63150 Tepic, Nay.
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Frequently asked questions about traveling from Guadalajara, MX to Mezcales by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Guadalajara to Mezcales?
The cheapest bus tickets from Guadalajara to Mezcales start from $47. The average price for this route is around $53. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Guadalajara to Mezcales?
The average bus trip duration from Guadalajara to Mezcales is 4h 30m, covering a distance of 125 miles (201 km). The quickest bus can get you there in 3h 20m and is operated by Primera Plus.
Which bus companies service the Guadalajara to Mezcales route?
Several major bus companies operate on this route with 33 buses available per day, including services from Futura, Primera Plus, Elite, Pacifico, Chihuahuenses, Nayar, Coras.
What is the earliest and latest departure time for the bus from Guadalajara to Mezcales?
The earliest bus departs from Guadalajara to Mezcales at 12:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Guadalajara to Mezcales?
A bus trip from Guadalajara to Mezcales generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Guadalajara to Mezcales?
According to Busbud customers, the highest-rated bus company on this route is Primera Plus, with an average rating of 4.1 out of 5 stars based on 14 reviews.
Which bus company has the best Wi-Fi from Guadalajara to Mezcales?
Based on reviews on Busbud, the bus company Primera Plus has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from Guadalajara to Mezcales?
According to Busbud traveler reviews, the most timely bus company on this route is Primera Plus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Guadalajara to Mezcales?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Primera Plus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Guadalajara, MX to Mezcales was searched and found on Feb 10, 2026 with a price of $49To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to Mezcales, as early as possible.
You can expect to pay from $49 to $147 for a bus ticket from Guadalajara, MX to Mezcales based on the last 2 days. You can expect to find the cheapest price for the trip at $49 which is on 2026-02-14.
Usually Primera Plus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
Top traveled bus routes
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