Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Houston Panama City recent customer reviews
staff is poorly to not driven whatsoever to provide a good customer service . they speak to everyone like there cattle being herded and feels depressing when at multiple stops asking for information on times or where to go is impossible and quite frankly a rude and unpleasant experience.need a whole rehaul of there employee to customer base experience cause it is empty and a rude and sometimes questionably racist sitiatuons.
2 out of 5 stars
David M.
Even though we had a late start, I still arrived in Florida on time. Very pleasant
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Houston, US to Panama City, US by bus
What is the travel distance from Houston to Panama City?
About 581 miles (936 km) separate Houston and Panama City.
What are the departure and arrival stations when taking the bus from Houston to Panama City?
The majority of buses traveling from Houston to Panama City start their journey at Hillcroft Ave & Southwest Freeway and wind up at Panama City Greyhound Bus Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Panama City?
Once in Panama City, you can start exploring the city and discover its surroundings. The top sights and things to do are Museo Antropologico Reina Torres De Arauz, The Panama Canal, Bird Watching, Casco Antiguo and Ancon Hill.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/22
No data
11/23
No data
Today
$63
11/25
$65
11/26
No data
11/27
No data
11/28
No data
11/29
$73
The cheapest trip from Houston, US to Panama City, US was searched and found on Nov 24, 2025 with a price of $63
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Panama City, US, as early as possible.
You can expect to pay from $63 to $115 for a bus ticket from Houston, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $65 which is on 2025-11-25.
The cheapest trip from Houston, US to Panama City, US was searched and found on Nov 24, 2025 with a price of $63
