Bus Tickets from Houston, US to Panama City, US

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TomorrowJul 25
from $120
SatJul 26
from $88
SunJul 27
from $86
MonJul 28
TueJul 29
from $83
WedJul 30
from $83
ThuJul 31
FriAug 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 25 at
    Departure city: Houston
    Departure location: Houston Bus Station
    Arrival time: July 26 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 25 at
    Departure city: Houston
    Departure location: Houston Bus Station
    Arrival time: July 26 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 25 at
    Departure city: Houston
    Departure location: Downtown Gray & Smith
    Arrival time: July 26 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 25 at
    Departure city: Houston
    Departure location: Downtown Gray & Smith
    Arrival time: July 26 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 25 at
    Departure city: Houston
    Departure location: Houston Uptown/Upper Kirby
    Arrival time: July 26 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Houston, US to Panama City, US: Trip Overview

Average ticket price$109
Average bus trip duration14h 35m
Number of daily buses4
Earliest bus departure9:15am
Distance577 miles (930 km)
Latest bus departure11:25pm

Houston to Panama City Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Houston to Panama City.

We make sure you can find a bus service from Houston to Panama City from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from Houston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Houston, US - Panama City, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/22
$69
07/23
$69
Today
$112
07/25
$112
07/26
$80
07/27
$78
07/28
No data
07/29
$75
busbud logoThe cheapest trip from Houston, US to Panama City, US was searched and found on Jul 22, 2025 with a price of $69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Panama City, US, as early as possible.

You can expect to pay from $69 to $160 for a bus ticket from Houston, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-07-29.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Houston to Panama City but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Houston to Panama City, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Houston to Panama City.

Tune out to the fine sounds of your best music playlist on your bus trip from Houston to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Houston, US by bus?

Bus from Houston, US to Panama City, US

Why choose Busbud?

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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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