Next departures for Lafayette to Chicago on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Next departures for Lafayette to Chicago on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Next departures for Lafayette to Chicago on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Next departures for Lafayette to Chicago on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Next departures for Lafayette to Chicago on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Next departures for Lafayette to Chicago on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Next departures for Lafayette to Chicago on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lafayette Bus Stop
Downtown Greyhound Station
Cheapest
Bus
Lafayette Bus Stop
Chicago 95Th & Dan Ryan
Fastest
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Bus
Lafayette Bus Stop
Downtown Greyhound Station
No tags
Last refresh of the prices: Today at 9:11 PM EST.
Compare 2 ways to go from Lafayette to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 2 hours 30 minutes and with fares starting at just $28, it presents an excellent value for a comfortable ride.
Users have expressed satisfaction with the service, highlighting that the bus ride was fast and comfortable as advertised. They appreciated the cleanliness of the bus, cool air conditioning throughout the journey, and found drivers to be friendly and professional.
FlixBus Lafayette Chicago recent customer reviews
I was informed the bus was late. I do not want to wait outside and cold so I decided to hang out in the lobby up an apartment complex however bus came and left without confirming all the passengers I had to repay to be on the next ride because it was third-party. No empathy or compassionate at all by the Customer Service at all.
1 out of 5 stars
Hassan N.
i enjoy the ride,the bus was nice and clean and the air was cool all the way,the driver was very friendly and professional.
5 out of 5 stars
Beverly W.
The bus was 1 hour and 17 minutes late. It was supposed to pick me up at 9:45 and it finally came at 11:02. I called the company three times during that period and they couldn’t tell me where the bus was. I am very dissatisfied with this service that wasted so much of my time. Completely unacceptable.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Lines, Inc. Lafayette Chicago recent customer reviews
I enjoyed the fact that I got to my destination safely, I didn’t enjoy the fact that this was my 13yo daughters’ first time riding & the driver was loudly being trained as well a intoxicated passenger having an argument with another passenger who asked him if he wanted to get shot for falling over on him which frightened my daughter & she was nervous the entire ride until they got off (before us). We normally drive & I wasn’t expecting that to be her first experience on a Greyhound travel bus so never again! At least not with her!
1 out of 5 stars
Fatima P.
Their bus to Chicago was terribly late. I was waiting in the cold with my luggage for my bus for around 50 minutes. Also, their onboard Wi-Fi did not work either.
2 out of 5 stars
Sebastian A.
Bus was more than 5 hr late, costumer service wasn't able to help or find solutions
Frequently asked questions about traveling from Lafayette, IN to Chicago by bus
How far is Lafayette from Chicago?
The distance between the two cities is 109 miles (175 km).
What are the departure and arrival stations when taking the bus from Lafayette to Chicago?
Most of the buses traveling from Lafayette to Chicago leave from CityBus Center and arrive at Downtown Greyhound Station. These are the primary departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Robie House, Willis Tower (Sears Tower), Architectural River Cruise, Cloud Gate and Museum of Contemporary Art.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$30
11/17
$28
Today
$25
11/19
$25
11/20
$25
11/21
$28
11/22
$28
11/23
$28
The cheapest trip from Lafayette, IN to Chicago was searched and found on Nov 18, 2025 with a price of $25
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, IN to Chicago, as early as possible.
You can expect to pay from $25 to $90 for a bus ticket from Lafayette, IN to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-11-19.
Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Lafayette, IN to Chicago?
The bus is the cheapest travel choice for this destination
The cheapest trip from Lafayette, IN to Chicago was searched and found on Nov 18, 2025 with a price of $25
The bus is the cheapest travel choice for this destination
