How much is the bus ticket from Indianapolis to Myrtle Beach?

The cheapest bus tickets from Indianapolis to Myrtle Beach start from $111. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Indianapolis to Myrtle Beach?

The average bus trip duration from Indianapolis to Myrtle Beach is 1d , covering a distance of 580 miles (936 km). The quickest bus can get you there in 1d and is operated by Greyhound .

Which bus companies service the Indianapolis to Myrtle Beach route?

Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Indianapolis to Myrtle Beach?

The earliest bus departs from Indianapolis to Myrtle Beach at 1:40pm. And the latest bus departs at 11:15pm.

What are the CO₂ emissions for the bus trip from Indianapolis to Myrtle Beach?

A bus trip from Indianapolis to Myrtle Beach generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Indianapolis to Myrtle Beach?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Indianapolis to Myrtle Beach?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Indianapolis to Myrtle Beach?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Indianapolis to Myrtle Beach?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Indianapolis to Myrtle Beach from $103 | Refundable Tickets

Next bus departures

Next departures for Indianapolis to Myrtle Beach on December 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	6:25pm	Downtown Transit Center	21h 25m	3:50pm	Bus Station	CheapestFastest
	Bus	3:50pm	Indianapolis Bus Station	1d	3:50pm	Bus Station	No tags

Next departures for Indianapolis to Myrtle Beach on December 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:50pm	Indianapolis Bus Station	1d	3:50pm	Bus Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	6:25pm	Downtown Transit Center	21h 25m	3:50pm	Bus Station	Fastest

Next departures for Indianapolis to Myrtle Beach on December 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	6:25pm	Downtown Transit Center	21h 25m	3:50pm	Bus Station	CheapestFastest
	Bus	3:50pm	Indianapolis Bus Station	1d	3:50pm	Bus Station	No tags

Next departures for Indianapolis to Myrtle Beach on December 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	6:25pm	Downtown Transit Center	21h 25m	3:50pm	Bus Station	CheapestFastest
	Bus	3:50pm	Indianapolis Bus Station	1d	3:50pm	Bus Station	No tags

Last refresh of the prices: Last Tuesday at 4:44 AM EST.

Get from Indianapolis to Myrtle Beach

This route is served by bus only

The journey takes about 1 day and with fares starting at just $111, it presents an excellent value for a comfortable ride.

2bus per day

1d Average Duration

580 milesDistance

23kgCO₂ emissions

Where are the popular stops in Indianapolis and Myrtle Beach?

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Stops in Myrtle Beach

A
Bus Station
511 7th Ave N, Myrtle Beach, SC 29577, USA
Visit page

Compare bus companies

Greyhound

3.5/587,442 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,676 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Indianapolis to Myrtle Beach by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Indianapolis to Myrtle Beach?
The cheapest bus tickets from Indianapolis to Myrtle Beach start from $111. The average price for this route is around $115. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Myrtle Beach?
The average bus trip duration from Indianapolis to Myrtle Beach is 1d , covering a distance of 580 miles (936 km). The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the Indianapolis to Myrtle Beach route?
Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Indianapolis to Myrtle Beach?
The earliest bus departs from Indianapolis to Myrtle Beach at 1:40pm. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Indianapolis to Myrtle Beach?
A bus trip from Indianapolis to Myrtle Beach generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Indianapolis to Myrtle Beach?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Myrtle Beach?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Indianapolis to Myrtle Beach?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Myrtle Beach?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/19

$148

12/20

$138

Today

$115

12/22

No data

12/23

No data

12/24

$103

12/25

$105

12/26

$117

The cheapest trip from Indianapolis to Myrtle Beach was searched and found on Dec 24, 2025 with a price of $103

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Myrtle Beach, as early as possible.

You can expect to pay from $103 to $148 for a bus ticket from Indianapolis to Myrtle Beach based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-12-24.