Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Jacksonville Bus Station | BILOXI | Cheapest | ||||
 | Bus | Jacksonville Bus Station | BILOXI | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Jacksonville Bus Station | BILOXI | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Jacksonville Bus Station | BILOXI | No tags |
Last refresh of the prices: Today at 6:20 AM EDT.
Get from Jacksonville to Biloxi
The journey takes about 18 hours 40 minutes and with fares starting at just COP 203,210, it presents an excellent value for a comfortable ride.
Bus stations and stops in Jacksonville and Biloxi
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Biloxi
- A
Love's
11332 Cedar Lake Rd, Biloxi, MS 39532, USA - B
Transit Center
820 Dr Martin Luther King Jr Blvd, Biloxi, MS 39530, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Jacksonville, FL to Biloxi by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Jacksonville to Biloxi?
The cheapest bus tickets from Jacksonville to Biloxi start from COP 203,210. The average price for this route is around COP 261,561. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Biloxi?
The average bus trip duration from Jacksonville to Biloxi is 18h 40m, covering a distance of 431 miles (695 km). The quickest bus can get you there in 12h 20m and is operated by Greyhound.
Which bus companies service the Jacksonville to Biloxi route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Jacksonville to Biloxi?
The earliest bus departs from Jacksonville to Biloxi at 8:00am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Biloxi?
A bus trip from Jacksonville to Biloxi generates an estimated 17.359925000000004 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Biloxi was searched and found on Sep 6, 2026 with a price of COP 230,196To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Biloxi, as early as possible.
You can expect to pay from COP 230,196 to COP 345,342 for a bus ticket from Jacksonville, FL to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at COP 230,196 which is on 2026-09-06.
