Bus Tickets from Jacksonville, FL to Buffalo, NY

Previously seen trips

Next departures for Jacksonville to Buffalo on October 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Jacksonville Bus Station
Niagara Frontier Transportation AuthorityNo tags
Greyhound + FlixBus
Jacksonville Bus Station
Buffalo (BUF) AirportNo tags
Greyhound
Jacksonville Bus Station
Niagara Frontier Transportation AuthorityNo tags
FlixBus
Jacksonville Bus Station
Niagara Frontier Transportation AuthorityNo tags
FlixBus
Jacksonville Bus Station
Buffalo (BUF) AirportNo tags

Accepted payments

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Compare 2 ways to go from Jacksonville to Buffalo

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 1 day, 7 hours 10 minutes and with fares starting at just $125, it presents an excellent value for a comfortable ride.

5bus per day
1d 7hAverage Duration
880 milesDistance
35kgCO₂ emissions
Bus
Average Price$125 - $356Average Duration1d 7h
35kg CO₂e
Train
Average Price$235 - $2,464Average Duration1d 4h
129kg CO₂e

Bus Jacksonville, FL to Buffalo, NY: Trip Overview

Average ticket price$171
Average bus trip duration1d 7h
Number of daily buses5
Earliest bus departure9:05am
Distance880 miles (1418 km)
Latest bus departure9:25pm

Jacksonville to Buffalo Bus

With Busbud, comparing and booking tickets for a bus from Jacksonville to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Jacksonville to Buffalo from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Buffalo from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Jacksonville, FL - Buffalo, NY

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/25
No data
10/26
$207
Today
No data
10/28
No data
10/29
No data
10/30
No data
10/31
No data
11/01
$138
busbud logoThe cheapest trip from Jacksonville, FL to Buffalo, NY was searched and found on Nov 1, 2025 with a price of $138

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Buffalo, NY, as early as possible.

You can expect to pay from $138 to $209 for a bus ticket from Jacksonville, FL to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $138 which is on 2025-11-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Jacksonville to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Buffalo, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Jacksonville to Buffalo.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Jacksonville to Buffalo.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Jacksonville, FL to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Buffalo, NY to Jacksonville, FL

You can also go to Buffalo, NY by train

Train from Jacksonville, FL to Buffalo, NY

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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