Bus Tickets from La Crosse, WI to Spokane

Previously seen trips

Next departures for La Crosse to Spokane on October 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Jefferson Lines
632 17th Street North
Spokane NorthNo tags
Jefferson Lines
La Crosse MTU Transit Center
Spokane NorthNo tags

Accepted payments

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Compare 2 ways to go from La Crosse to Spokane.

Bus
Average Price$199 - $199Average Duration1d 23h
52kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$282 - $352Average Duration1d 8h
189kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from La Crosse to Spokane

Among the sustainable travel choices, the train stands out as the good way to reach Spokane. The journey takes about 1 day, 8 hours 40 minutes and with fares starting at just $282, it presents an excellent value for a comfortable ride.

2train per day
1d 8hAverage Duration
$282Cheapest ticket
189kgCO₂ emissions

Bus La Crosse, WI to Spokane: Trip Overview

Average ticket price$199
Average bus trip duration1d 23h
Number of daily buses2
Earliest bus departure12:25pm
Distance1281 miles (2065 km)
Latest bus departure12:50pm

La Crosse to Spokane Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from La Crosse to Spokane.

Bus service from La Crosse to Spokane will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from La Crosse to Spokane, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip La Crosse, WI - Spokane

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/03
No data
10/04
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Today
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10/06
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10/07
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10/08
$193
10/09
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10/10
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busbud logoThe cheapest trip from La Crosse, WI to Spokane was searched and found on Oct 8, 2025 with a price of $193

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Spokane, as early as possible.

You can expect to pay from $193 to $193 for a bus ticket from La Crosse, WI to Spokane based on the last 2 days. You can expect to find the cheapest price for the trip at $193 which is on 2025-10-08.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from La Crosse to Spokane but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from La Crosse to Spokane, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from La Crosse to Spokane that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from La Crosse to Spokane.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from La Crosse, WI to Spokane?

busbud logoThe bus is the cheapest travel choice for this destination

You can also go to Spokane by train

Train from La Crosse, WI to Spokane

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