Bus Tickets from Saint Paul, US to Chicago

Find affordable bus tickets from Saint Paul, US to Chicago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJul 26
from $74
TomorrowJul 27
from $70
MonJul 28
from $63
TueJul 29
from $61
WedJul 30
from $63
ThuJul 31
from $61
FriAug 1
from $63
SatAug 2
from $63

Next departures to Chicago

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 27 at
    Departure city: Saint Paul
    Departure location: Union Depot
    Arrival time: July 27 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 27 at
    Departure city: Saint Paul
    Departure location: Union Depot
    Arrival time: July 27 at
    Destination city: Chicago
    Destination location: N Cumberland Ave
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 27 at
    Departure city: Saint Paul
    Departure location: Union Depot
    Arrival time: July 27 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: July 27 at
    Departure city: Saint Paul
    Departure location: Union Depot
    Arrival time: July 27 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 27 at
    Departure city: Saint Paul
    Departure location: Union Depot
    Arrival time: July 27 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Saint Paul to Chicago.

Bus
Average Price$49 - $395Average Duration9h 15m
14kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average Price$47 - $569Average Duration7h 55m
51kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from Saint Paul to Chicago

Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 7 hours 55 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.

4train per day
7h 55mAverage Duration
$47Cheapest ticket
51kgCO₂ emissions

Bus Saint Paul, US to Chicago: Trip Overview

Average ticket price$63
Average bus trip duration9h 15m
Number of daily buses17
Earliest bus departure12:45am
Distance346 miles (557 km)
Latest bus departure11:30pm

Saint Paul to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Saint Paul to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Saint Paul to Chicago from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from Saint Paul, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Saint Paul, US - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/24
$64
07/25
$136
Today
$66
07/27
$62
07/28
$55
07/29
$53
07/30
$55
07/31
$53
busbud logoThe cheapest trip from Saint Paul, US to Chicago was searched and found on Jul 29, 2025 with a price of $53

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Saint Paul, US to Chicago, as early as possible.

You can expect to pay from $53 to $136 for a bus ticket from Saint Paul, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-07-29.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Saint Paul to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Saint Paul to Chicago, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Saint Paul to Chicago.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Saint Paul to Chicago.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Saint Paul, US to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Saint Paul, US by bus?

Bus from Saint Paul, US to Chicago

You can also go to Chicago by train

Train from Saint Paul, US to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular bus departures from Saint Paul

Popular bus departures to Saint Paul

Continue your journey from Chicago