Next bus departures

Next departures for Lafayette to Chicago on October 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:30pm	TA Travel Center - Lafayette	1d 2h	11:30pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus Wifi Toilet Power outlets	9:30pm	TA Travel Center - Lafayette	23h 5m	8:35pm	Downtown Greyhound Station	Fastest
	Bus Wifi Toilet Power outlets	9:25pm	Lafayette Transit System	1d 6h	4:20am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	9:30pm	TA Travel Center - Lafayette	1d 10h	8:00am	537-517 W. Jackson Blvd	No tags
	Bus Wifi Toilet Power outlets	10:35pm	Lafayette Transit System	1d 9h	8:00am	537-517 W. Jackson Blvd	No tags

Next departures for Lafayette to Chicago on October 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	5:25pm	Lafayette Transit System	1d 6h	11:30pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus Wifi Toilet Power outlets	9:30pm	TA Travel Center - Lafayette	23h 5m	8:35pm	Downtown Greyhound Station	Fastest
	Bus Wifi Toilet Power outlets	2:00am	Lafayette Transit System	1d 6h	8:25am	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus Wifi Toilet Power outlets	5:25pm	Lafayette Transit System	1d 3h	8:35pm	Downtown Greyhound Station	No tags
	Bus Wifi Toilet Power outlets	9:35am	Lafayette Transit System	1d 4h	2:10pm	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	2:25am	TA Travel Center - Lafayette	1d 9h	11:30am	Downtown Greyhound Station	No tags
	Bus Wifi Toilet Power outlets	9:25pm	Lafayette Transit System	1d 6h	4:20am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus Wifi Toilet Power outlets	2:25am	TA Travel Center - Lafayette	1d 11h	1:45pm	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Yesterday at 8:34 AM CDT.

Compare 2 ways to go from Lafayette to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 6 hours 55 minutes and with fares starting at just $97, it presents an excellent value for a comfortable ride.

20bus per day

1d 6hAverage Duration

835 milesDistance

34kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$97 - $403	Average Duration1d 6h	CO₂ emissions 34kg CO₂e
Train	Average Price$204 - $334	Average Duration1d 14h	CO₂ emissions 123kg CO₂e

Bus stations and stops in Lafayette and Chicago

Stops in Lafayette

A
TA Travel Center - Lafayette
1701 N University Ave, Lafayette, LA 70507, USA
Visit page
B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501
C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/588,240 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/516,299 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit, Wanda Coach

Frequently asked questions about traveling from Lafayette, LA to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Lafayette to Chicago?
The cheapest bus tickets from Lafayette to Chicago start from $97. The average price for this route is around $163. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lafayette to Chicago?
The average bus trip duration from Lafayette to Chicago is 1d 6h, covering a distance of 835 miles (1347 km). The quickest bus can get you there in 23h 5m and is operated by FlixBus.
Which bus companies service the Lafayette to Chicago route?
Several major bus companies operate on this route with 20 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Lafayette to Chicago?
The earliest bus departs from Lafayette to Chicago at 1:00am. And the latest bus departs at 10:35pm.
What are the CO₂ emissions for the bus trip from Lafayette to Chicago?
A bus trip from Lafayette to Chicago generates an estimated 33.66117499999999 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lafayette to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88236 reviews.
Which bus company has the best Wi-Fi from Lafayette to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Lafayette to Chicago?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Lafayette to Chicago?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/16

No data

10/17

$207

Today

$178

10/19

$186

10/20

$110

10/21

No data

10/22

$118

10/23

No data

The cheapest trip from Lafayette, LA to Chicago was searched and found on Oct 20, 2026 with a price of $110

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to Chicago, as early as possible.

You can expect to pay from $110 to $299 for a bus ticket from Lafayette, LA to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2026-10-20.