- Louisville to Florence buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Louisville, KY | Florence, SC | No tags | ||||
![]() | Bus | Louisville, KY | Bus station | No tags | ||||
FlixBus + Greyhound | Bus | Louisville, KY | Florence, SC | No tags | ||||
FlixBus + Greyhound | Bus | Louisville, KY | Bus station | No tags | ||||
![]() | Bus | Louisville, KY | Bus station | No tags |
Get from Louisville to Florence
The journey takes about 22 hours 30 minutes and with fares starting at just $111, it presents an excellent value for a comfortable ride.
Where are the popular stops in Louisville and Florence?
Stops in Louisville
- A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about traveling from Louisville to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Louisville to Florence?
The cheapest bus tickets from Louisville to Florence start from $111. The average price for this route is around $132. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Louisville to Florence?
The average bus trip duration from Louisville to Florence is 22h 30m, covering a distance of 436 miles (703 km). The quickest bus can get you there in 17h 25m and is operated by Greyhound.
Which bus companies service the Louisville to Florence route?
What is the earliest and latest departure time for the bus from Louisville to Florence?
The earliest bus departs from Louisville to Florence at 1:35am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Louisville to Florence?
A bus trip from Louisville to Florence generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Louisville to Florence?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5696 reviews.
Which bus company has the best Wi-Fi from Louisville to Florence?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Louisville to Florence?
According to Busbud traveller reviews, the most timely bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Louisville to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Top traveled bus routes
People from around the world trust Busbud
Popular bus departures from Louisville
- Find bus tickets from Louisville to Memphis
- Louisville to Detroit bus times and fares
- How to travel from Louisville to Cincinnati
- Find bus tickets from Louisville to Indianapolis
- Louisville to Atlanta bus times and fares
- How to travel from Louisville to Chicago
- Find bus tickets from Louisville to New York City







