Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Lyon Lyon Perrache Bus Station | Lampugnano | Cheapest | |||||
 | Perrache | Lampugnano bus station | Fastest | |||||
| Perrache | Lampugnano bus station | No tags | |||||
| Lyon Lyon Perrache Bus Station | Lampugnano | No tags | |||||
| Perrache | Lampugnano bus station | No tags |
Last refresh of the prices: Today at 12:42 PM CET.
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Compare 3 ways to go from Lyon to Milano
Among the sustainable travel choices, the carpool stands out as the good way to reach Milano. The journey takes about 5 hours 10 minutes and with fares starting at just $33, it presents an excellent value for a comfortable ride.
Bus Lyon to Milano: Trip Overview
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Lyon to Milano Bus
Busbud helps you find a bus from Lyon to Milano. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Lyon to Milano from the most reliable bus companies operating this trip.
Discover how much the bus trip from Lyon to Milano will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Lyon and Milano?
Frequently asked questions for your trip Lyon - Milano
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lyon to Milano was searched and found on Nov 10, 2025 with a price of $21To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Milano, as early as possible.
You can expect to pay from $21 to $136 for a bus ticket from Lyon to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $21 which is on 2025-11-10.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lyon and Milano!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Milano, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Milano will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Lyon to Milano, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top traveled bus routes
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Popular Buses Connecting Lyon
Buses Leaving from Lyon
- Bus from Lyon to Marseille
- Bus Lyon - Saint-Étienne
- Lyon - Lens
- Bus from Lyon to Reims
- Bus Lyon - Rennes
- Lyon - Auxerre
- Bus from Lyon to L'Alpe-d'Huez
- Bus Lyon - Les Deux Alpes
- Lyon - Chamonix Mont Blanc
- Bus from Lyon to Tignes
- Bus Lyon - Nice
- Lyon - Grenoble
- Bus from Lyon to Annecy
- Bus Lyon - Avignon
- Lyon - Val-d'Isère
Buses Going to Lyon
- Bus from Saint-Étienne to Lyon
- Bus Nice - Lyon
- Le Havre - Lyon
- Bus from Brest to Lyon
- Bus Utrecht - Lyon
- Montpellier - Lyon
- Bus from L'Alpe-d'Huez to Lyon
- Bus Les Deux Alpes - Lyon
- Chamonix Mont Blanc - Lyon
- Bus from Marseille to Lyon
- Bus Grenoble - Lyon
- Toulouse - Lyon
- Bus from Tignes to Lyon
- Bus Avignon - Lyon
- Annecy - Lyon
Popular Buses Connecting Milano
Buses Leaving from Milano
- Bus from Milano to Sanremo
- Bus Milano - Zürich
- Milano - Bisceglie
- Bus from Milano to Bari
- Bus Milano - Verona
- Milano - Monza
- Bus from Milano to Genoa
- Bus Milano - Como
- Milano - Venice
- Bus from Milano to Breuil-Cervinia
- Bus Milano - Florence
- Milano - Courmayeur
- Bus from Milano to Naples
- Bus Milano - Padova
- Milano - Passo del Tonale
Buses Going to Milano
- Bus from Outlet to Milano
- Bus London - Milano
- Loreto - Milano
- Bus from Bratislava to Milano
- Bus Bologna - Milano
- Amsterdam - Milano
- Bus from Turin to Milano
- Bus Venice - Milano
- Genoa - Milano
- Bus from Florence to Milano
- Bus Como - Milano
- Padova - Milano
- Bus from Naples to Milano
- Bus Taranto - Milano
- Courmayeur - Milano
Popular routes in this country
- Bus from Beauvais to Paris
- Bus Lille - Paris
- Marseille - Nice
- Bus from Paris to Rennes
- Bus Paris - Strasbourg
- Paris - Montpellier
- Bus from Chamonix Mont Blanc to Annecy
- Bus Toulouse - Paris
- Nice - Marseille
- Bus from Annecy to Chamonix Mont Blanc
- Bus Nice - Paris
- Caen - Paris
- Bus from Rennes to Paris
- Bus Paris - Rouen
- Strasbourg - Paris