Bus Tickets from Madrid to Brussels

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TodayMay 22
from $56
TomorrowMay 23
from $69
SatMay 24
from $61
SunMay 25
from $63
MonMay 26
from $57
TueMay 27
from $81
WedMay 28
from $75
ThuMay 29

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 23 at
    Departure city: Madrid
    Departure location: Estación Sur
    Arrival time: May 24 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 23 at
    Departure city: Madrid
    Departure location: Estación Sur
    Arrival time: May 24 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: Madrid
    Departure location: Estación Sur
    Arrival time: May 24 at
    Destination city: Brussels
    Destination location: Brussels-South (Gare du Midi)
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: Madrid
    Departure location: Estación Sur
    Arrival time: May 24 at
    Destination city: Brussels
    Destination location: Brussels North Train Station
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:

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Compare 2 ways to go from Madrid to Brussels.

Bus
Average Price$54 - $284Average Duration23h 45m
33kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$71 - $175Average Duration17h 30m
55kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Madrid to Brussels

Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 17 hours 30 minutes and with fares starting at just $71, it presents an excellent value for a comfortable ride.

1carpool per day
17h 30mAverage Duration
$71Cheapest ticket
55kgCO₂ emissions

Bus Madrid to Brussels: Trip Overview

Average ticket price$116
Average bus trip duration23h 45m
Number of daily buses16
Earliest bus departure12:40am
Distance823 miles (1327 km)
Latest bus departure11:45pm

Madrid to Brussels Bus

With Busbud, comparing and booking tickets for a bus from Madrid to Brussels is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Madrid to Brussels will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Brussels from Madrid, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Madrid - Brussels

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/20
$141
05/21
$82
Today
$56
05/23
$69
05/24
$60
05/25
$63
05/26
$57
05/27
$81
busbud logoThe cheapest trip from Madrid to Brussels was searched and found on May 22, 2025 with a price of $56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Brussels, as early as possible.

You can expect to pay from $56 to $177 for a bus ticket from Madrid to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $57 which is on 2025-05-26.

Usually Flixbus (ES) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Madrid to Brussels.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Madrid to Brussels, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Madrid to Brussels.

Make a music playlist for your bus ride from Madrid to Brussels, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Madrid by bus?

Bus from Madrid to Brussels

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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