Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mendoza Terminal | Estación Terminal de Ómnibius, Santa Fe | Cheapest | ||||
| Bus | Mendoza Terminal | Estación Terminal de Ómnibius, Santa Fe | Fastest | ||||
 | Bus | Mendoza Terminal | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
 | Bus | Mendoza Terminal | Estación Terminal de Ómnibius, Santa Fe | No tags | ||||
| Bus | Mendoza Terminal | Estación Terminal de Ómnibius, Santa Fe | No tags |
Last refresh of the prices: Yesterday at 12:54 PM -03.
Get from Mendoza to Santa Fe
The journey takes about 14 hours 45 minutes and with fares starting at just $61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mendoza and Santa Fe?
Stops in Mendoza
- AAv. Gdor. Ricardo Videla, Mendoza, Argentina
- BAv. Gobernador Ricardo Videla , M5519 Mendoza, Argentina
- CAcceso A Aeropuerto Internacional Gabrielli F. J., Las Heras, Mendoza, Argentina
- DChile 1124, 5500 Mendoza, Argentina
- E
Parada de Autobuses de Mendoza - Nogoli
Nogoli 699, M5501HVC Godoy Cruz, Mendoza, Argentina - F
Vistalba 3020
Vistalba 3020, Godoy Cruz, Mendoza, Argentina
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Frequently asked questions about traveling from Mendoza, AR to Santa Fe, AR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mendoza to Santa Fe?
The cheapest bus tickets from Mendoza to Santa Fe start from $61. The average price for this route is around $78. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mendoza to Santa Fe?
The average bus trip duration from Mendoza to Santa Fe is 14h 45m, covering a distance of 482 miles (777 km). The quickest bus can get you there in 14h 25m and is operated by Flechabus.
Which bus companies service the Mendoza to Santa Fe route?
Several major bus companies operate on this route with 3 buses available per day, including services from 20 de Junio, Andesmar, Flechabus, Pool Mendoza Rosario, Tramat.
What is the earliest and latest departure time for the bus from Mendoza to Santa Fe?
The earliest bus departs from Mendoza to Santa Fe at 9:00am. And the latest bus departs at 9:30pm.
What are the CO₂ emissions for the bus trip from Mendoza to Santa Fe?
A bus trip from Mendoza to Santa Fe generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mendoza to Santa Fe?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 586 reviews.
Which bus company has the best Wi-Fi from Mendoza to Santa Fe?
Based on reviews on Busbud, the bus company 20 de Junio has the best Wi-Fi rating with a score of 2.3.
Which bus company has the most timely service from Mendoza to Santa Fe?
According to Busbud traveller reviews, the most timely bus company on this route is 20 de Junio, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Mendoza to Santa Fe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mendoza, AR to Santa Fe, AR was searched and found on Dec 12, 2025 with a price of $57To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza, AR to Santa Fe, AR, as early as possible.
You can expect to pay from $57 to $93 for a bus ticket from Mendoza, AR to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-12-19.
Usually 20 de Junio will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
