Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | San Luquitas | CheapestFastest |
Last refresh of the prices: Last Tuesday at 4:06 PM PST.
Compare 2 ways to go from Mexicali to San Ysidro
Among the sustainable travel choices, the carpool stands out as the good way to reach San Ysidro. The journey takes about 2 hours 30 minutes and with fares starting at just $11, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$187 - $187 | Average Duration20h 10m | 4kg CO₂e | ||
Carpool | Average Price$11 - $13 | Average Duration2h 30m | 6kg CO₂e |
Where are the popular stops in Mexicali and San Ysidro?
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
Compare bus companies
Autobuses Aguila offers 1 daily buses from Mexicali to San Ysidro. Though the average price for this trip is $187, you can find tickets starting at $187. The trip between the two cities usually takes about 1210.
Frequently asked questions about traveling from Mexicali to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mexicali to San Ysidro?
The cheapest bus tickets from Mexicali to San Ysidro start from $187. The average price for this route is around $187. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mexicali to San Ysidro?
The average bus trip duration from Mexicali to San Ysidro is 20h 10m, covering a distance of 93 miles (149 km). The quickest bus can get you there in 20h 10m and is operated by Autobuses Aguila.
Which bus companies service the Mexicali to San Ysidro route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Mexicali to San Ysidro?
The earliest bus departs from Mexicali to San Ysidro at 5:30pm. And the latest bus departs at 5:30pm.
What are the CO₂ emissions for the bus trip from Mexicali to San Ysidro?
A bus trip from Mexicali to San Ysidro generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexicali to San Ysidro, CA was searched and found on Dec 11, 2025 with a price of $174To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to San Ysidro, CA, as early as possible.
You can expect to pay from $174 to $176 for a bus ticket from Mexicali to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $174 which is on 2025-12-14.
