How much is the bus ticket from Milano to Brindisi?

The cheapest bus tickets from Milano to Brindisi start from $21. The average price for this route is around $80. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Milano to Brindisi?

The average bus trip duration from Milano to Brindisi is 17h 15m, covering a distance of 548 miles (884 km). The quickest bus can get you there in 12h 40m and is operated by MarinoBus .

Which bus companies service the Milano to Brindisi route?

Several major bus companies operate on this route with 25 buses available per day, including services from FlixBus , Itabus , MarinoBus .

What is the earliest and latest departure time for the bus from Milano to Brindisi?

The earliest bus departs from Milano to Brindisi at 12:30am. And the latest bus departs at 11:55pm.

What are the CO₂ emissions for the bus trip from Milano to Brindisi?

A bus trip from Milano to Brindisi generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Milano to Brindisi?

According to Busbud customers, the highest-rated bus company on this route is MarinoBus , with an average rating of 4.1 out of 5 stars based on 893 reviews.

Which bus company has the best Wi-Fi from Milano to Brindisi?

Based on reviews on Busbud, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.2.

Which bus company has the most timely service from Milano to Brindisi?

According to Busbud traveller reviews, the most timely bus company on this route is MarinoBus , with a punctuality rating of 4.3 out of 5 stars.

Which bus company has the cleanest buses from Milano to Brindisi?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus , with a cleanliness rating of 4.3 out of 5 stars.

Bus Milano to Brindisi from $20 | Refundable Tickets

Next bus departures

Next departures for Milano to Brindisi on November 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:50pm	Lampugnano	19h 45m	4:35pm	Brindisi Bus Stop	Cheapest
Bus	9:05pm	Milan Via Giuseppe Impastato	12h 40m	9:45am	Brindisi Bus Stop	Fastest
Bus	7:40pm	Milan Malpensa Airport T1, Bus station	14h 5m	9:45am	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags

Next departures for Milano to Brindisi on December 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:25pm	Lampugnano	14h 35m	10:00am	Brindisi Bus Stop	Cheapest
Bus	9:05pm	Milan Via Giuseppe Impastato	12h 40m	9:45am	Brindisi Bus Stop	Fastest
Bus	7:40pm	Milan Malpensa Airport T1, Bus station	14h 5m	9:45am	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags

Next departures for Milano to Brindisi on December 2
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:10pm	Milan Via Giuseppe Impastato	13h 50m	10:00am	Brindisi Bus Stop	Cheapest
Bus	9:05pm	Milan Via Giuseppe Impastato	12h 40m	9:45am	Brindisi Bus Stop	Fastest
Bus	7:40pm	Milan Malpensa Airport T1, Bus station	14h 5m	9:45am	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags

Next departures for Milano to Brindisi on December 3
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:25pm	Lampugnano	14h 35m	10:00am	Brindisi Bus Stop	Cheapest
Bus	9:05pm	Milan Via Giuseppe Impastato	12h 40m	9:45am	Brindisi Bus Stop	Fastest
Bus	7:40pm	Milan Malpensa Airport T1, Bus station	14h 5m	9:45am	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags
Bus	3:35pm	Milan (Malpensa Aeroporto Terminal 1)	19h 45m	11:20am	Brindisi Bus Stop	No tags

Next departures for Milano to Brindisi on December 4
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:25pm	Lampugnano	14h 35m	10:00am	Brindisi Bus Stop	Cheapest
Bus	9:05pm	Milan Via Giuseppe Impastato	12h 40m	9:45am	Brindisi Bus Stop	Fastest
Bus	7:40pm	Milan Malpensa Airport T1, Bus station	14h 5m	9:45am	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags
Bus	6:00am	Lampugnano	17h 25m	11:25pm	Brindisi Bus Stop	No tags

Last refresh of the prices: Yesterday at 3:42 PM CET.

Compare 2 ways to go from Milano to Brindisi

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Brindisi. The journey takes about 11 hours and with fares starting at just $52, it presents an excellent value for a comfortable ride.

1carpool per day

11hAverage Duration

553 milesDistance

37kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$21 - $219	Average Duration17h 15m	CO₂ emissions 22kg CO₂e
Carpool	Average Price$52 - $87	Average Duration11h	CO₂ emissions 37kg CO₂e

Where are the popular stops in Milano and Brindisi?

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page
B
Linate Airport
Visit page
C
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
D
Malpensa Airport
Visit page
E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Stops in Brindisi

A
Brindisi Bus Stop
Via Giuseppe Maria Galanti, 8, 72100 Brindisi BR, Italy
Visit page
B
Brindisi Airport
Visit page
C
Fermata dell'autobus Brindisi
Viale Arno, 72100 Brindisi BR, Italy
D
Porto
Viale Regina Margherita, 72100 Brindisi BR, Italy
E
Brindisi Rione Casale
Via Osanna, 97, 72100 Brindisi BR, Italy
F
Via Palmiro Togliatti
Via Palmiro Togliatti, 11, 72100 Brindisi BR, Italy

Compare bus companies

FlixBus

3.5/511,476 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Itabus

4/5947 reviews

Staff4.3

Timeliness3

Cleanliness4.3

Wifi3.1

MarinoBus

4/5896 reviews

Staff4.7

Timeliness4.3

Cleanliness4.3

Wifi3.3

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Milano to Brindisi by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Milano to Brindisi?
The cheapest bus tickets from Milano to Brindisi start from $21. The average price for this route is around $80. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Brindisi?
The average bus trip duration from Milano to Brindisi is 17h 15m, covering a distance of 548 miles (884 km). The quickest bus can get you there in 12h 40m and is operated by MarinoBus.
Which bus companies service the Milano to Brindisi route?
Several major bus companies operate on this route with 25 buses available per day, including services from FlixBus, Itabus, MarinoBus.
What is the earliest and latest departure time for the bus from Milano to Brindisi?
The earliest bus departs from Milano to Brindisi at 12:30am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Milano to Brindisi?
A bus trip from Milano to Brindisi generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Milano to Brindisi?
According to Busbud customers, the highest-rated bus company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 893 reviews.
Which bus company has the best Wi-Fi from Milano to Brindisi?
Based on reviews on Busbud, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.2.
Which bus company has the most timely service from Milano to Brindisi?
According to Busbud traveller reviews, the most timely bus company on this route is MarinoBus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Milano to Brindisi?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/28

$42

11/29

$36

Today

$52

12/01

$30

12/02

$20

12/03

$24

12/04

$30

12/05

$65

The cheapest trip from Milano to Brindisi was searched and found on Dec 2, 2025 with a price of $20

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Brindisi, as early as possible.

You can expect to pay from $20 to $180 for a bus ticket from Milano to Brindisi based on the last 2 days. You can expect to find the cheapest price for the trip at $20 which is on 2025-12-02.