Bus Tickets from Orlando to Winston-Salem

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TomorrowJun 24
from $113
WedJun 25
from $117
ThuJun 26
FriJun 27
from $100
SatJun 28
SunJun 29
MonJun 30
from $142
TueJul 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 24 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 25 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 25 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 25 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Orlando
    Departure location: The Florida Mall
    Arrival time: June 25 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Orlando to Winston-Salem.

Bus
Average Price$79 - $263Average Duration16h 15m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$123 - $123Average Duration1d 17h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Orlando to Winston-Salem

Among the sustainable travel choices, the bus stands out as the good way to reach Winston-Salem. The journey takes about 16 hours 15 minutes and with fares starting at just $79, it presents an excellent value for a comfortable ride.

4bus per day
16h 15mAverage Duration
$79Cheapest ticket
21kgCO₂ emissions

Bus Orlando to Winston-Salem: Trip Overview

Average ticket price$171
Average bus trip duration16h 15m
Number of daily buses4
Earliest bus departure5:15am
Distance526 miles (847 km)
Latest bus departure10:40pm

Orlando to Winston-Salem Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Winston-Salem.

We make sure you can find a bus service from Orlando to Winston-Salem from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Winston-Salem from Orlando, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Orlando - Winston-Salem

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/21
No data
06/22
No data
Today
$143
06/24
$121
06/25
$112
06/26
No data
06/27
No data
06/28
No data
busbud logoThe cheapest trip from Orlando to Winston-Salem was searched and found on Jun 25, 2025 with a price of $112

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Winston-Salem, as early as possible.

You can expect to pay from $112 to $143 for a bus ticket from Orlando to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $112 which is on 2025-06-25.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Winston-Salem but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Orlando to Winston-Salem, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to Winston-Salem.

Make a music playlist for your bus ride from Orlando to Winston-Salem, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Orlando by bus?

Bus from Orlando to Winston-Salem

You can also go to Winston-Salem by train

Train from Orlando to Winston-Salem

Why choose Busbud?

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