Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Tampa Bus Station | Cheapest | ||||
| Bus | Panama City Beach Station | Tampa Bus Station | Fastest |
Last refresh of the prices: Yesterday at 11:33 PM CST.
Get from Panama City to Tampa
The journey takes about 10 hours 40 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Tampa?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Panama City Tampa recent customer reviews
It was quite nice, although my seat smelled vaugely of urine. Other than that, great time.
Aeron J.
Salimos una hora después... esperaba estar a las 630 en tampa y llegue a las 930 tuve q pasar por relajarse y Orlando.... mÑNa
Lina P.
Great improvement in hygiene. But they don't keep to Time .
Ethel O.
Frequently asked questions about traveling from Panama City, US to Tampa by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Tampa?
The cheapest bus tickets from Panama City to Tampa start from $62. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Tampa?
The average bus trip duration from Panama City to Tampa is 10h 40m, covering a distance of 253 miles (407 km). The quickest bus can get you there in 9h 40m and is operated by Greyhound.
Which bus companies service the Panama City to Tampa route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Panama City to Tampa?
The earliest bus departs from Panama City to Tampa at 7:25am. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from Panama City to Tampa?
A bus trip from Panama City to Tampa generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Tampa was searched and found on Dec 3, 2025 with a price of $72To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Tampa, as early as possible.
You can expect to pay from $72 to $114 for a bus ticket from Panama City, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $72 which is on 2025-12-10.
Top traveled bus routes
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Popular bus departures from Panama City
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